Propyl 3-{[(2-chlorophenoxy)acetyl]amino}benzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Propyl 3-{[(2-chlorophenoxy)acetyl]amino}benzoate
• 英文别名: propyl 3-[[2-(2-chlorophenoxy)acetyl]amino]benzoate
• 化学式: C₁₈H₁₈ClNO₄
• 分子量: 347.8
• InChiKey: UYUJISUELMSBKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  64.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Compounds for inhibiting secretory leukocyte protease inhibitor (SLPI)
  申请人：The General Hospital Corporation

  公开号：US11351144B2

  公开（公告）日：2022-06-07

  This invention relates to compounds that are useful for inhibiting the secretion of secretory leukocyte protease inhibitor (SLPI) in a subject. Methods of inhibiting metastasis of cancer and methods of treating cancer in a subject are also provided.

  本发明涉及可用于抑制受试者体内分泌型白细胞蛋白酶抑制剂（SLPI）分泌的化合物。本发明还提供了抑制癌症转移的方法和治疗受试者癌症的方法。
• Compounds For Inhibiting Secretory Leukocyte Protease Inhibitor (SLPI)
  申请人：The General Hospital Corporation

  公开号：US20210196666A1

  公开（公告）日：2021-07-01

  This invention relates to compounds that are useful for inhibiting the secretion of secretory leukocyte protease inhibitor (SLPI) in a subject. Methods of inhibiting metastasis of cancer and methods of treating cancer in a subject are also provided.
• [EN] COMPOUNDS FOR INHIBITING SECRETORY LEUKOCYTE PROTEASE INHIBITOR (SLPI)<br/>[FR] COMPOSÉS POUR INHIBER UN INHIBITEUR DE PROTÉASE LEUCOCYTAIRE SÉCRÉTOIRE (SLPI)
  申请人：MASSACHUSETTS GEN HOSPITAL

  公开号：WO2019074895A1

  公开（公告）日：2019-04-18

  This invention relates to compounds that are useful for inhibiting the secretion of secretory leukocyte protease inhibitor (SLPI) in a subject. Methods of inhibiting metastasis of cancer and methods of treating cancer in a subject are also provided.