3-chloro-N-({4-[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]phenyl}carbamothioyl)-1-benzothiophene-2-carboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-chloro-N-({4-[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]phenyl}carbamothioyl)-1-benzothiophene-2-carboxamide
• 英文别名: 3-chloro-N-[[4-[4-(thiophene-2-carbonyl)piperazin-1-yl]phenyl]carbamothioyl]-1-benzothiophene-2-carboxamide
• 化学式: C₂₅H₂₁ClN₄O₂S₃
• 分子量: 541.1
• InChiKey: MFZYFVCBKPDGIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  35
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  153
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Methods of treating or preventing Zika virus infection
  申请人：NUtech Ventures

  公开号：US11135219B2

  公开（公告）日：2021-10-05

  This document relates to methods and materials for treating a mammal having a Zika virus (ZIKV) infection. For example, a composition including one or more non-nucleoside RNA polymerase inhibitors can be administered to a mammal having, or at risk of developing, a ZIKV infection to treat the mammal

  本文涉及治疗哺乳动物寨卡病毒（ZIKV）感染的方法和材料。例如，可将包括一种或多种非核苷类 RNA 聚合酶抑制剂的组合物施用给患有或可能患有 ZIKV 感染的哺乳动物，以治疗该哺乳动物
• METHODS OF TREATING OR PREVENTING ZIKA VIRUS INFECTION
  申请人：NUtech Ventures

  公开号：US20190167670A1

  公开（公告）日：2019-06-06

  This document relates to methods and materials for treating a mammal having a Zika virus (ZIKV) infection. For example, a composition including one or more non-nucleoside RNA polymerase inhibitors can be administered to a mammal having, or at risk of developing, a ZIKV infection to treat the mammal