5-氯-5-甲基壬酮 | 67282-24-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 5-氯-5-甲基壬酮
• 英文名称: 5-chloro-5-methyl-nonane
• 英文别名: 5-Chlor-5-methyl-nonan；5-Chloro-5-methylnonane
• CAS: 67282-24-0
• 化学式: C₁₀H₂₁Cl
• mdl: MFCD00060780
• 分子量: 176.73
• InChiKey: FYIAPWZQRBQNSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  萘 、 5-氯-5-甲基壬酮 在 二硫化碳 、 三氯化铝 作用下， 生成 1-(1-butyl-1-methyl-pentyl)-naphthalene
  参考文献：
  名称：

  Petrow; Kurbsski, Zhurnal Obshchei Khimii, 1944, vol. 14, p. 492

  摘要：

  DOI：
• 作为产物：
  描述：

  5-甲基-5-壬醇 在 盐酸 作用下， 生成 5-氯-5-甲基壬酮
  参考文献：
  名称：

  The Treatment of Facial Verrucae With the Pulsed Dye Laser

  摘要：

  AbstractObjectives/Hypothesis To evaluate the treatment of facial verrucae with the pulsed dye laser.Study Design A prospective, nonrandomized, nonblinded pilot study evaluating the treatment of facial verrucae with the pulsed dye laser.Methods Twelve patients with facial verrucae (four recalcitrant) were identified and followed in the study in the setting of a tertiary referral center. The treatment consisted of the flash‐lamp pumped pulsed dye laser (585 mn) with a spot size of 5 mm at fluences between 9.0 and 13 J/cm2. Each lesion received one or two pulses with 2 mm of surrounding normal skin included in the treatment. One patient had paring prior to pulse treatment. The patients were examined 3 to 4 weeks after each procedure, and clinical assessment of the lesion was documented.Results Patient ages ranged from 18 to 47 years. Four patients had refractory lesions, and eight patients had never undergone previous treatment. All 12 patients had full resolution of their facial warts after one to three treatment sessions. No complications such as scarring, alopecia, or recurrence were encountered. Follow‐up ranged from 10 to 33 months.Conclusions Pulsed dye laser therapy is highly effective and safe therapy for facial verrucae. This method appears to selectively destroy warts without damaging surrounding skin.

  DOI：

  10.1097/00005537-200209000-00007

文献信息

• Ruechardt,C. et al., Chemische Berichte, 1978, vol. 111, p. 2179 - 2189
  作者：Ruechardt,C. et al.

  DOI：——

  日期：——
• Isomerization of Olefins. I. Conversion of t-Butylethylene, unsym-Methylisopropylethylene and Tetramethylethylene to Equilibrium Mixtures of the Three Olefins¹
  作者：K. C. Laughlin、C. W. Nash、Frank C. Whitmore

  DOI：10.1021/ja01321a056

  日期：1934.6
• Organic Thiol Stabilizers and Plasticizers for Halogen-Containing Polymers
  申请人：Starnes H William

  公开号：US20070161728A1

  公开（公告）日：2007-07-12

  A novel organic thiol stabilizer for PVC is described herein. Specifically, this novel thiol stabilizer for PVC is dipentaerythritol hexakis(mercaptoacetate). The organic thiol stabilizer of the present invention, when blended with halogen-containing polymers such as PVC, or derivatives thereof, provides advantages in cost and/or performance relative to existing organic stabilizers for PVC.
• US7553897B2
  申请人：——

  公开号：US7553897B2

  公开（公告）日：2009-06-30
• The Treatment of Facial Verrucae With the Pulsed Dye Laser
  作者：Hannah Vargas、Christopher R. Hove、Marsha L. Dupree、Edwin F. Williams

  DOI：10.1097/00005537-200209000-00007

  日期：2002.9

  AbstractObjectives/Hypothesis To evaluate the treatment of facial verrucae with the pulsed dye laser.Study Design A prospective, nonrandomized, nonblinded pilot study evaluating the treatment of facial verrucae with the pulsed dye laser.Methods Twelve patients with facial verrucae (four recalcitrant) were identified and followed in the study in the setting of a tertiary referral center. The treatment consisted of the flash‐lamp pumped pulsed dye laser (585 mn) with a spot size of 5 mm at fluences between 9.0 and 13 J/cm2. Each lesion received one or two pulses with 2 mm of surrounding normal skin included in the treatment. One patient had paring prior to pulse treatment. The patients were examined 3 to 4 weeks after each procedure, and clinical assessment of the lesion was documented.Results Patient ages ranged from 18 to 47 years. Four patients had refractory lesions, and eight patients had never undergone previous treatment. All 12 patients had full resolution of their facial warts after one to three treatment sessions. No complications such as scarring, alopecia, or recurrence were encountered. Follow‐up ranged from 10 to 33 months.Conclusions Pulsed dye laser therapy is highly effective and safe therapy for facial verrucae. This method appears to selectively destroy warts without damaging surrounding skin.

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