N~1~-(2-Bromo-4-methylphenyl)-4-chlorobutanamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N~1~-(2-Bromo-4-methylphenyl)-4-chlorobutanamide
• 英文别名: N-(2-bromo-4-methylphenyl)-4-chlorobutanamide
• 化学式: C₁₁H₁₃BrClNO
• mdl: MFCD01648145
• 分子量: 290.58
• InChiKey: KHLUCHDDSFYQQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• HPK1 INHIBITORS AND USES THEREOF
  申请人：QILU REGOR THERAPEUTICS INC.

  公开号：US20220389037A1

  公开（公告）日：2022-12-08

  Provided herein is a compound represented by structural formula (I-0) or formula (II): or a pharmaceutically acceptable salt or a stereoisomer thereof useful for treating diseases (such as cancer) that are treatable by inhibiting HPK1 activity.
• [EN] HPK1 INHIBITORS AND USES THEREOF<br/>[FR] INHIBITEURS DE HPK1 ET LEURS UTILISATIONS
  申请人：QILU REGOR THERAPEUTICS INC

  公开号：WO2021000935A1

  公开（公告）日：2021-01-07

  Provided herein is a compound represented by structural formula (I-0) or formula (II): or a pharmaceutically acceptable salt or a stereoisomer thereof useful for treating diseases (such as cancer) that are treatable by inhibiting HPK1 activity.