2-pyridinesulfonylisocyanate | 90139-98-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-pyridinesulfonylisocyanate
• 英文别名: N-(oxomethylidene)pyridine-2-sulfonamide
• CAS: 90139-98-3
• 化学式: C₆H₄N₂O₃S
• 分子量: 184.175
• InChiKey: DODXZJLHTDSXCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  84.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-氨基-4-甲氧基-6-甲基嘧啶 、 2-pyridinesulfonylisocyanate 在 盐酸 、 sodium hydroxide 作用下， 以 水 、 乙腈 为溶剂， 生成 N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-2-pyridinesulfonamide
  参考文献：
  名称：

  Agricultural pyridinesulfonamides

  摘要：

  N-(杂环胺甲酰基)吡啶磺胺类化合物对植物生长的调节以及作为草甘膦的前除草剂和后除草剂具有用处。

  公开号：

  US04435206A1
• 作为产物：
  描述：

  1--3-butyl-harnstoff 、 光气 以 邻二甲苯 为溶剂， 以to yield 2-pyridinesulfonylisocyanate的产率得到2-pyridinesulfonylisocyanate
  参考文献：
  名称：

  Agricultural pyridinesulfonamides

  摘要：

  N-(杂环氨基甲酰基)吡啶磺酰胺可用于调节植物生长，并作为除草剂的前期和后期应用。

  公开号：

  US04522645A1

文献信息

• Herbicidal pyridinesulfonamides, preparation and use thereof and compositions containing them
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0013480A2

  公开（公告）日：1980-07-23

  Pyridinesulfonamides of a general formula and their agriculturally suitable salts wherein: R1 and R2 are H or various substituents; R3 and R. are independently H or CH3; W is O or S: and R is a pyrimidyl or triazinyl residue which may be substituted; are of interest as herbicides for preemergence or post- emergence application and for regulating plant growth. The compounds can be made e.g. by reacting an appropriate pyridylsulfonyl isocyanate or isothiocyanate with an appropriate amino- or methylamino-substituted pyrimidine or triazine. The compounds can be formulated for use in conventional manner.

  通式为吡啶磺酰胺及其农业上适用的盐类，其中：R1 和 R2 为 H 或各种取代基；R3 和 R 独立地为 H 或 CH3；W 为 O 或 S；R 为可被取代的嘧啶基或三嗪基残基。 这些化合物可用作除草剂，用于萌芽前或萌芽后施药以及调节植物生长。 例如，可通过将适当的吡啶磺酰基异氰酸酯或异硫氰酸酯与适当的氨基或甲氨基取代的嘧啶或三嗪反应来制造这些化合物。 这些化合物可按常规方式配制使用。
• Herbicidal sulfonamides, and preparation and use thereof
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0015683A1

  公开（公告）日：1980-09-17

  Sulfonamides of the general formula wherein R is optionally substituted phenyl or optionally substituted pyridyl; R, is R12 is selected from various organic groups; X is H, CH3, CH30, Cl or OCH2CH3; Y is CH2 or O; and W is 0 or S; and their agriculturally suitable salts, exhibit herbicidal activity. The compounds can be formulated into herbicidal compositions in conventional manner. The compounds of formula I may made by reacting a corresponding sulfonyl thiocyanate or isothiocyanate of the formula RS02NCW with an appropriate aminopyrimidine derivative. The compound of formula II may be made by appropriate alkylation of an alkali metal or alkaline earth metal salt of a corresponding sulfonylthiourea.

  通式如下的磺酰胺类化合物 其中 R 是任选取代的苯基或任选取代的吡啶基； R，是 R12 选自各种有机基团 X 是 H、CH3、CH30、Cl 或 OCH2CH3； Y 是 CH2 或 O；以及 W 是 0 或 S；以及它们在农业上适用的盐类，具有除草活性。这些化合物可按常规方法配制成除草组合物。式 I 的化合物可通过式 RS02NCW 的相应磺酰基硫氰酸盐或异硫氰酸盐与适当的氨基嘧啶衍生物反应制得。式 II 的化合物可通过相应磺酰硫脲的碱金属或碱土金属盐的适当烷基化制得。
• Herbicidal sulfonamides, preparation and use thereof, and compositions containing them
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0023140A2

  公开（公告）日：1981-01-28

  Compounds of the general formula wherein A is B is Cl or Br: R is carboxylic ester, amide, Cl, CF3, N02 or various sulfur containing groups: R1 is H, halogen, NO2, CH3, OCH, or CF,; X and Z are independently H, CH3, Bf, Cl, OCH3, CH2CH3, CH2OCH3 or OCH2CH3; and Y is halogen, CN, NO or various organic groups; and their agriculturally suitable salts; exhibit potent herbicidal activity. Some can also be used to regulate plant growth. The compounds can be made by reacting the appropriately substituted benzenesulfonyl or pyridinesulfonyl isocyanate with the appropriate 2-aminopyrimidine they can be formulated for agricultural use in conventional manner. Compounds wherein R is carboxyl are of interest as intermediates for the preparation of the compounds (I).

  通式如下的化合物 其中 A 是 B 是 Cl 或 Br R 是羧酸酯、酰胺、Cl、CF3、N02 或各种含硫基团： R1 是 H、卤素、NO2、CH3、OCH 或 CF； X 和 Z 独立地为 H、CH3、Bf、Cl、OCH3、CH2CH3、CH2OCH3 或 OCH2CH3；以及 Y 是卤素、CN、NO 或各种有机基团；以及它们在农业上适用的盐；具有强大的除草活性。有些还可用于调节植物生长。这些化合物可以通过适当取代的苯磺酰基或吡啶磺酰基异氰酸酯与适当的 2-氨基嘧啶反应制成，它们可以按常规方式配制成农用产品。 R 为羧基的化合物可作为制备化合物 (I) 的中间体。
• Substituted pyridinesulfonylisocyanates and preparation thereof
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0049554A2

  公开（公告）日：1982-04-14

  Substituted pyridinesulfonylisocyanates of the formula wherein R1 is halogen, CH3, NO2 or alkoxycarbonyl are valuable intermeidates for the preparation of herbicidal pyridinesulfonylurea derivatives. They may be prepared by reacting a corresponding R,-substituted N-(alkylaminocarbonyl)pyridinesulfonamide with phosgene.

  式中 R1 为卤素、CH3、NO2 或烷氧基羰基的取代吡啶磺酰基异氰酸酯是制备除草型吡啶磺酰脲衍生物的重要中间体。 它们可通过相应的 R-取代 N-（烷基氨基羰基）吡啶磺酰胺与光气反应制备。
• Herbicidal sulfonamides
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0046677A2

  公开（公告）日：1982-03-03

  Compounds of the formula: (wherein A is an unsubstituted or substituted phenyl, phenoxy, pyridyl, furyl or thienyl group; W is 0 or S; X is CH3'C2H5, Cl, OCH3, OC2H6, N(CH3)2 or SCH3; Y is H, CH3 or C2H5 and Z is H or CH3) and the agriculturally suitable salts thereof possess herbicidal activity. They are also of interest as plant growth regulants and may be used to modify plant growth beneficially as well as to selectively control weeds in crops such as wheat, barley, cotton and soybeans. The compounds may be formulated for use in conventional manner. The compounds may be prepared by a variety of processes e.g. by reacting an appropriately substituted isocyanate or isothiocyanate with an appropriately substituted furo [2,3-d]pyrimidine amine. The furo [2,3-d] pyrimidine amines may be prepared by reaction of an appropriate keto-ester with guanidine carbonate or by reaction of an appropriate dichloropyrimidine with an alkali metal hydroxide. Compounds corresponding to formula I but in which A represents a benzyl, furyl or thienyl group substituted by a carboxyl or carboxylic acid salt moiety are novel intermediates.

  式中的化合物： (其中 A 是未取代或取代的苯基、苯氧基、吡啶基、呋喃基或噻吩基；W 是 0 或 S；X 是 CH3'C2H5、Cl、OCH3、OC2H6、N(CH3)2 或 SCH3；Y 是 H、CH3 或 C2H5，Z 是 H 或 CH3）及其农业上适用的盐类具有除草活性。作为植物生长调节剂，它们也具有重要意义，可用于有益地改变植物生长，以及选择性地控制小麦、大麦、棉花和大豆等作物中的杂草。这些化合物可按常规方法配制使用。 这些化合物可以通过多种工艺制备，例如，将适当取代的异氰酸酯或异硫氰酸盐与适当取代的呋喃 [2,3-d]嘧啶胺反应。呋喃[2,3-d]嘧啶胺可通过适当的酮酯与碳酸胍反应或适当的二氯嘧啶与碱金属氢氧化物反应制备。 对应于式 I 但其中 A 代表被羧基或羧酸盐基取代的苄基、呋喃基或噻吩基的化合物是新型中间体。