[4-(4-Benzoylbenzoyl)oxy-4-oxobutanimidoyl] 4-benzoylbenzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [4-(4-Benzoylbenzoyl)oxy-4-oxobutanimidoyl] 4-benzoylbenzoate
• 英文别名: [4-(4-benzoylbenzoyl)oxy-4-oxobutanimidoyl] 4-benzoylbenzoate
• 化学式: C₃₂H₂₃NO₇
• 分子量: 533.5
• InChiKey: BQMCJOQQXLIRDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  40
• 可旋转键数：
  13
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  128
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• [EN] PHOTOCHEMICAL ACTIVATION OF SURFACES FOR ATTACHING BIOMATERIAL<br/>[FR] ACTIVATION PHOTOCHIMIQUE DE SURFACES POUR L'ATTACHE DE BIOMATIÈRE
  申请人：PHILADELPHIA CHILDREN HOSPITAL

  公开号：WO2014039799A2

  公开（公告）日：2014-03-13

  A water-soluble photo-activatable polymer including : a photo-activatable group adapted to be activated by an irradiation source and to form a covalent bond between the water-soluble photo-activatable polymer and a matrix having at least one carbon; a reactive group adapted to covalently react with a biomaterial for subsequent delivery of the biomaterial to a cell; a hydrophilic group; and a polymer precursor. A composition including a monomolecular layer of the water-soluble photo-activatable polymer and a matrix having at least one carbon, wherein the monomolecular layer is covalently attached to the matrix by a covalent bond between the photo-activatable group and the at least one carbon. The composition further includes a biomaterial having a plurality of active, groups, wherein the biomaterial is covalently attached to the monomolecular layer by covalent bonding between the active groups and reactive groups. Also provided is a method for delivery of a biomaterial to a cell.
• [EN] PHOTOREACTIVE AND CLEAVABLE PROBES FOR TAGGING BIOMOLECULES<br/>[FR] SONDES PHOTORÉACTIVES ET CLIVABLES PERMETTANT LE MARQUAGE DE BIOMOLÉCULES
  申请人：ACADEMIA SINICA

  公开号：WO2021188978A1

  公开（公告）日：2021-09-23

  Compositions including photoreactive and cleavable probes and methods of using the probes. The probes may include a tag conjugatable to a label, a cleavable linker linkable to a bait molecule, and a light activated warhead. The compositions and methods may be useful for analyzing biomolecules.