1-(Isothiocyanatomethyl)-3-pentan-3-ylbenzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(Isothiocyanatomethyl)-3-pentan-3-ylbenzene
• 英文别名: 1-(isothiocyanatomethyl)-3-pentan-3-ylbenzene
• 化学式: C₁₃H₁₇NS
• 分子量: 219.35
• InChiKey: ZULDXPDDYSEJFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  44.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
  申请人：Genentech, Inc.

  公开号：US20140079721A1

  公开（公告）日：2014-03-20

  The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
• HINGE MODIFIED ANTIBODY FRAGMENTS AND METHODS OF MAKING
  申请人：GENENTECH, INC.

  公开号：US20200308304A1

  公开（公告）日：2020-10-01

  The instant disclosure provides antibody fragments (e.g., Fab and F(ab′) 2 ) having reduced or no reactivity towards pre-existing anti-hinge antibodies (AHA) and compositions comprising such antibody fragments, as well as methods of making and using such antibody fragments and compositions.
• US8871911B2
  申请人：——

  公开号：US8871911B2

  公开（公告）日：2014-10-28
• US9029511B2
  申请人：——

  公开号：US9029511B2

  公开（公告）日：2015-05-12