1-Tert-butyl-3-[4-[3-(4-methoxyphenyl)phenoxy]phenyl]urea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Tert-butyl-3-[4-[3-(4-methoxyphenyl)phenoxy]phenyl]urea
• 英文别名: 1-tert-butyl-3-[4-[3-(4-methoxyphenyl)phenoxy]phenyl]urea
• 化学式: C₂₄H₂₆N₂O₃
• 分子量: 390.5
• InChiKey: FXZPYRWCFDXEQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  59.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• METHODS AND COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS AND VIRAL INFECTIONS
  申请人：University College Dublin National University Of Ireland, Dublin

  公开号：EP2838519A2

  公开（公告）日：2015-02-25
• [EN] METHODS AND COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS AND VIRAL INFECTIONS<br/>[FR] MÉTHODES ET COMPOSÉS DE TRAITEMENT DE TROUBLES PROLIFÉRATIFS ET D'INFECTIONS VIRALES
  申请人：UNIV DUBLIN

  公开号：WO2013156861A2

  公开（公告）日：2013-10-24

  The invention generally relates to methods and compounds for treating proliferative disorders, viral infections, or both. In some embodiments, the invention provides an anticancer or antiviral compound including a substituted nitro phenoxy phenyl, a sulfonylurea, and an alkyl group. In some embodiments, the invention provides a method of treating a proliferative disorder or a viral infection including administering an anticancer or antiviral compound that binds to a thromboxane receptor, has preferential binding for either TPalpha (TPα) or TPbeta (ΤΡβ) receptor subtype.