2-[[(2-methoxybenzoyl)amino]methyl]-N-[3-(trifluoromethyl)phenyl]benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[[(2-methoxybenzoyl)amino]methyl]-N-[3-(trifluoromethyl)phenyl]benzamide
• 化学式: C₂₃H₁₉F₃N₂O₃
• 分子量: 428.4
• InChiKey: LQMHSGUTNHVAML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  67.4
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• MODULATORS OF THE RELAXIN RECEPTOR 1
  申请人：The United States of America, as Represented by The Secretary, Department of Health and Human Services

  公开号：EP2844345A1

  公开（公告）日：2015-03-11
• [EN] MODULATORS OF THE RELAXIN RECEPTOR 1<br/>[FR] MODULATEURS DU RÉCEPTEUR DE RELAXINE 1
  申请人：US HEALTH

  公开号：WO2013165606A1

  公开（公告）日：2013-11-07

  Disclosed are modulators of the human relaxin receptor 1, for example, of formula (I), wherein A, R1, and R2 are as defined herein, that are useful in treating mammalian relaxin receptor 1 mediated facets of human health, e.g., cardiovascular disease. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the disclosure, and a method for therapeutic intervention in a facet of mammalian health that is mediated by a human relaxin receptor 1.