[(2R,3R,4R,5R)-3,4-bis[(4-chlorobenzoyl)oxy]-5-chlorooxyoxolan-2-yl]methyl 4-chlorobenzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(2R,3R,4R,5R)-3,4-bis[(4-chlorobenzoyl)oxy]-5-chlorooxyoxolan-2-yl]methyl 4-chlorobenzoate
• 化学式: C₂₆H₁₈Cl₄O₈
• 分子量: 600.2
• InChiKey: BICZWFKBJZYBIM-PIXQIBFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  38
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  97.4
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• [EN] A POSITRON EMISSION TOMOGRAPHY PROBE TO MONITOR SELECTED SUGAR METABOLISM IN VIVO<br/>[FR] SONDE DE TOMOGRAPHIE PAR ÉMISSION DE POSITRONS DESTINÉE À SURVEILLER LE MÉTABOLISME D'UN SUCRE SÉLECTIONNÉ IN VIVO
  申请人：UNIV CALIFORNIA

  公开号：WO2013170085A1

  公开（公告）日：2013-11-14

  The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.

  本发明披露了选定的核糖异构体，这些异构体可用作PET探针（例如[18F]-2-氟-2-脱氧-阿拉伯糖）。这些PET探针可用于监测生理过程，包括核糖代谢，或者选择性地观察体内的某些组织/器官。本发明还提供了制备和使用这些探针的方法。
• POSITRON EMISSION TOMOGRAPHY PROBE TO MONITOR SELECTED SUGAR METABOLISM IN VIVO
  申请人：The Regents of the University of California

  公开号：US20150133777A1

  公开（公告）日：2015-05-14

  The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metabolism and/or to selectively observe certain tissue/organs in vivo. The invention disclosed herein further provides methods for making and using such probes.
• US9592309B2
  申请人：——

  公开号：US9592309B2

  公开（公告）日：2017-03-14