(2S)-6-amino-2-(2,4-dinitrophenyl)hexanoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2S)-6-amino-2-(2,4-dinitrophenyl)hexanoic acid
• 化学式: C12H15N3O6
• 分子量: 297.26
• InChiKey: UGADIMSLTFSREY-JTQLQIEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  155
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• [EN] NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF<br/>[FR] NOUVEAUX INHIBITEURS DE LIPASE, SUBSTRATS RAPPORTEURS ET LEURS UTILISATIONS
  申请人：UNIV NORTHEASTERN

  公开号：WO2013177492A2

  公开（公告）日：2013-11-28

  The invention provides for novel lipase inhibitors, and compositions and devices comprising the same. The invention further provides for methods for treatment of disorders comprising administration of novel diacylglycerol lipase inhibitors, and compositions and devices comprising said inhibitors. In some embodiments, the disorders are pancreatitis, obesity, shock or pancreatic necrosis. The invention further provides for novel ether lipid reporter compounds and methods of assaying enzymatic activity comprising contacting a compound with a novel ether lipid reporter compound.