4,4,5,6,6-Pentafluorononan-5-amine

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 4,4,5,6,6-Pentafluorononan-5-amine
• 英文别名: 4,4,5,6,6-pentafluorononan-5-amine
• 化学式: C₉H₁₆F₅N
• 分子量: 233.22
• InChiKey: VWPPYJRHULPXRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• UNIQUELY TAGGED REARRANGED ADAPTIVE IMMUNE RECEPTOR GENES IN A COMPLEX GENE SET
  申请人：Adaptive Biotechnologies Corporation

  公开号：EP2861761A1

  公开（公告）日：2015-04-22
• METHOD OF IDENTIFYING ADAPTIVE IMMUNE RECEPTOR PAIRS
  申请人：Adaptive Biotechnologies Corporation

  公开号：EP2971105B1

  公开（公告）日：2018-08-01
• Uniquely Tagged Rearranged Adaptive Immune Receptor Genes in a Complex Gene Set
  申请人：Adaptive Biotechnologies Corporation

  公开号：US20140322716A1

  公开（公告）日：2014-10-30

  Compositions and methods are disclosed for uniquely tagging each rearranged gene segment that encodes a T cell receptor (TCR) and/or an immunoglobulin (Ig), in a DNA (or mRNA or cDNA reverse transcribed therefrom) sample from lymphoid cells. These and related embodiments permit accurate, high throughput quantification of distinct TCR and/or Ig encoding sequences. Also provided are compositions and methods for quantitatively sequencing the genes that encode both chains of a TCR or Ig heterodimer in a single cell, for example, to characterize the degree of T or B cell clonality in a sample.
• [EN] UNIQUELY TAGGED REARRANGED ADAPTIVE IMMUNE RECEPTOR GENES IN A COMPLEX GENE SET<br/>[FR] GÈNES DE RÉCEPTEUR IMMUNITAIRE ADAPTATIF RÉORGANISÉS À MARQUAGE UNIQUE DANS UN ENSEMBLE GÉNIQUE COMPLEXE
  申请人：ADAPTIVE BIOTECHNOLOGIES CORP

  公开号：WO2013188831A1

  公开（公告）日：2013-12-19

  Compositions and methods are disclosed for uniquely tagging each rearranged gene segment that encodes a T cell receptor (TCR) and/or an immunoglobulin (Ig), in a DNA (or mRNA or cDNA reverse transcribed therefrom) sample from lymphoid cells. These and related embodiments permit accurate, high throughput quantification of distinct TCR and/or Ig encoding sequences. Also provided are compositions and methods for quantitatively sequencing the genes that encode both chains of a TCR or Ig heterodimer in a single cell, for example, to characterize the degree of T or B cell clonality in a sample.
• [EN] UNIQUELY TAGGED REARRANGED ADAPTIVE IMMUNE RECEPTOR GENES IN A COMPLEX GENE SET<br/>[FR] GÈNES DE RÉCEPTEUR DE L'IMMUNITÉ ACQUISE RÉARRANGÉS À ÉTIQUETTE UNIQUE DANS UN ENSEMBLE COMPLEXE DE GÈNES
  申请人：ADAPTIVE BIOTECHNOLOGIES CORP

  公开号：WO2014145992A1

  公开（公告）日：2014-09-18

  Compositions and methods are disclosed for uniquely tagging each rearranged gene segment that encodes a T cell receptor (TCR) and/or an immunoglobulin (Ig), in a DNA (or mRNA or cDNA reverse transcribed therefrom) sample from lymphoid cells. These and related embodiments permit accurate, high throughput quantification of distinct TCR and/or Ig encoding sequences. Also provided are compositions and methods for quantitatively sequencing the genes that encode both chains of a TCR or Ig heterodimer in a single cell, for example, to characterize the degree of T or B cell clonality in a sample.