(2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 化学式: C34H40N4O12S2
• 分子量: 760.8
• InChiKey: XDMQGUVIXVRIKZ-YPMBQRQPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  52
• 可旋转键数：
  10
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  261
• 氢给体数：
  4
• 氢受体数：
  14

文献信息

• POTENTIATION OF ANTIBIOTIC TREATMENT WITH A PROTEIN-LIPID COMPLEX
  申请人：The Research Foundation for the State University of New York

  公开号：EP2869831A2

  公开（公告）日：2015-05-13
• [EN] POTENTIATION OF ANTIBIOTIC TREATMENT WITH A PROTEIN-LIPID COMPLEX<br/>[FR] POTENTIALISATION D'UN TRAITEMENT ANTIBIOTIQUE AVEC UN COMPLEXE PROTÉINE-LIPIDE
  申请人：UNIV NEW YORK STATE RES FOUND

  公开号：WO2014008465A2

  公开（公告）日：2014-01-09

  Provided are compositions and methods for potentiating the effect of antibiotics. The compositions comprise a non-covalent complex of alpha-lactalbumin and fatty acid. The fatty acids are cis, unsaturated, C14 to C20 fatty acids. The complex and antibiotic can be administered to an individual together or separately. The antibiotic may be one to which resistance has developed.