[EN] CELL ATTACHMENT COATINGS AND METHODS USING PHOSPHOROUS-CONTAINING PHOTOREAGENT<br/>[FR] REVÊTEMENTS DE FIXATION CELLULAIRE ET PROCÉDÉS À L'AIDE D'UN PHOTORÉACTIF CONTENANT DU PHOSPHORE
申请人:SURMODICS INC
公开号:WO2014004997A1
公开(公告)日:2014-01-03
Cell attachment coatings for articles such as implantable medical devices and cell culture vessels are disclosed. The coatings include an intermediate coater layer which includes a phosphorous-containing component that is bonded in the coating by reacted photoreactive functional groups. The coating also include a second coated layer including an immobilized ECM protein or peptide that includes an active portion of an ECM protein that is able to serve as an outer layer to contact cells during use. The coatings promoted enhanced cell binding and growth.