methyl 6-[(2-tert-butyl-4-chloro-5-hydroxy-3-oxo-4H-pyridazin-1-yl)oxymethyl]pyridine-3-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: methyl 6-[(2-tert-butyl-4-chloro-5-hydroxy-3-oxo-4H-pyridazin-1-yl)oxymethyl]pyridine-3-carboxylate
• 化学式: C₁₆H₂₀ClN₃O₅
• 分子量: 369.8
• InChiKey: OCWKBJSBVYCLHZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  92.2
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS
  申请人：Lantheus Medical Imaging, Inc.

  公开号：EP2882719A2

  公开（公告）日：2015-06-17
• [EN] COMPOSITIONS, METHODS, AND SYSTEMS OF THE SYNTHESIS AND USE OF IMAGING AGENTS<br/>[FR] COMPOSITIONS, PROCÉDÉS ET SYSTÈMES DE SYNTHÈSE, ET UTILISATION D'AGENTS D'IMAGERIE
  申请人：LANTHEUS MEDICAL IMAGING INC

  公开号：WO2014026079A2

  公开（公告）日：2014-02-13

  The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.