2,5-dihydro-1H-thiopyrano[4,3-b]pyridin-8-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,5-dihydro-1H-thiopyrano[4,3-b]pyridin-8-ol
• 化学式: C₈H₉NOS
• 分子量: 167.23
• InChiKey: GLGVZDUQGWVVCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  57.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• HPPD VARIANTS AND METHODS OF USE
  申请人：Bayer CropScience LP

  公开号：EP2895601A1

  公开（公告）日：2015-07-22
• [EN] HPPD VARIANTS AND METHODS OF USE<br/>[FR] VARIANTS HPPD ET LEURS PROCÉDÉS D'UTILISATION
  申请人：BAYER CROPSCIENCE LP

  公开号：WO2014043435A1

  公开（公告）日：2014-03-20

  Compositions and methods for conferring herbicide tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.
• [EN] HPPD VARIANTS AND METHODS OF USE<br/>[FR] VARIANTS D'HPPD ET PROCÉDÉS D'UTILISATION
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2015135881A1

  公开（公告）日：2015-09-17

  In the present invention, HPPD enzymes and plants containing them showing a full tolerance against several classes of HPPD-inhibitors are described. A set of HPPD enzymes have been designed which have either no or only a significantly reduced affinity to HPPD inhibitors and, at the same time, the rate of dissociation of the HPPD inhibitors of the enzyme is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors. In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.
• [EN] HPPD VARIANTS AND METHODS OF USE<br/>[FR] VARIANTS DE LA HPPD ET LEURS PROCÉDÉS D'UTILISATION
  申请人：BASF AGRICULTURAL SOLUTIONS SEED LLC

  公开号：WO2018165091A1

  公开（公告）日：2018-09-13

  Compositions and methods for conferring herbicide tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.