1,2-Dimethyl-1-(trifluoromethyl)cyclopentane

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1,2-Dimethyl-1-(trifluoromethyl)cyclopentane
• 英文别名: 1,2-dimethyl-1-(trifluoromethyl)cyclopentane
• 化学式: C₈H₁₃F₃
• 分子量: 166.18
• InChiKey: QCNWBQSPJWPJFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] INHIBITORS OF HEPATITIS C VIRUS<br/>[FR] INHIBITEURS DU VIRUS DE L'HÉPATITE C
  申请人：GILEAD SCIENCES INC

  公开号：WO2014008285A1

  公开（公告）日：2014-01-09

  Compounds of Formula I are disclosed, As well as pharmaceutically acceptable salts thereof. Methods of using said compounds and pharmaceutical compositions containing said compounds are also disclosed.

  化合物I的结构已经披露，以及其药用盐。还披露了使用这些化合物的方法和含有这些化合物的药物组合物。
• INHIBITORS OF HEPATITIS C VIRUS
  申请人：Gilead Sciences, Inc.

  公开号：EP3159345A1

  公开（公告）日：2017-04-26

  Compounds of Formula (IV), as well as pharmaceutically acceptable salts thereof, are disclosed: The compounds are useful in the treatment of Hepatitis C infections.

  本研究公开了式（IV）化合物及其药学上可接受的盐类： 这些化合物可用于治疗丙型肝炎感染。
• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：Universal Display Corporation

  公开号：EP3613751A1

  公开（公告）日：2020-02-26

  A compound comprising: a ligand LA of Formula I wherein, RA represents mono to the maximum allowable substitutions; X1 to X4 are each independently CR or N; RA, R, R1, and R2 are each independently selected from the group consisting of hydrogen or a substituent selected from the group consisting of deuterium, halogen, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, aryl, heteroaryl, acyl, carboxylic acid, ether, ester, nitrile, isonitrile, sulfanyl, sulfinyl, sulfonyl, phosphino, and combinations thereof;at least one of R1 and R2 has the formula of ---L1-G1 ; L1 is an organic linker or a direct bond, G1 is a substituted cycloalkyl group, or a substituted or unsubstituted multicyclic group; at least one RA is not hydrogen; LA is coordinated to Ir;Ir can be coordinated to other ligands; LA can be linked with other ligands to comprise a tridentate, tetradentate, pentadentate, or hexadentate ligand; and any two substituents can be joined or fused together to form a ring, with the proviso that R1 and R2 are not joined to form a ring.

  一种化合物，包括 式 I 的配体 LA 其中，RA 代表单取代基至最大允许取代基；X1 至 X4 各自独立地为 CR 或 N；RA、R、R1 和 R2 各自独立地选自氢或选自以下组别的取代基：氘、卤素、烷基、环烷基、杂环烷基、杂环烷基、芳烷基、烷氧基、芳氧基、芳氧基、烷氧基、芳氧基、芳氧基、芳氧基、芳氧基、芳氧基、芳氧基、芳氧基、烷氧基、芳氧基、氨基、硅烷基、烯基、环烯基、杂烯基、炔基、芳基、杂芳基、酰基、羧酸、醚、酯、腈、异腈、硫酰基、亚磺酰基、磺酰基、膦及其组合；R1和R2中至少有一个具有---L1-G1式；L1是有机连接体或直接键，G1是取代的环烷基或取代或未取代的多环基团；至少有一个RA不是氢；LA与Ir配位；Ir可与其他配体配位；LA 可以与其他配体连接，组成三齿、四齿、五齿或六齿配体；任意两个取代基可以连接或融合在一起形成一个环，但 R1 和 R2 不能连接形成一个环。