2-(2-methoxyethoxy)-3-pyridylsulfonamide | 90811-02-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(2-methoxyethoxy)-3-pyridylsulfonamide
• 英文别名: 2-(2-methoxyethoxy)pyridine-3-sulfonamide
• CAS: 90811-02-2
• 化学式: C₈H₁₂N₂O₄S
• 分子量: 232.26
• InChiKey: KYVIIXQBVLNMQA-UHFFFAOYSA-N

物化性质

• 沸点：
  417.3±55.0 °C(Predicted)
• 密度：
  1.327±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  99.9
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  2-氯-吡啶-3-磺酸酰胺 在 盐酸 作用下， 以 乙二醇甲醚 为溶剂， 生成 2-(2-methoxyethoxy)-3-pyridylsulfonamide
  参考文献：
  名称：

  Novel sulfonylureas

  摘要：

  本发明涉及公式I的N-吡啶磺酰基-N'-嘧啶基和-N'-三嗪基脲化合物，其中A是C.sub.3-C.sub.6炔基、被卤素取代的C.sub.1-C.sub.6烷基、C.sub.1-C.sub.4烷氧基、C.sub.1-C.sub.4烷基硫基、C.sub.1-C.sub.4烷基亚硫酰基、C.sub.1-C.sub.4烷基磺酰基、C.sub.1-C.sub.4卤代烷氧基、C.sub.1-C.sub.4卤代烷基硫基、C.sub.1-C.sub.4卤代烷基亚硫酰基或C.sub.1-C.sub.4卤代烷基磺酰基，或者是未取代或被C.sub.1-C.sub.6烷基取代的C.sub.2-C.sub.4烯基基团，或是未取代或被卤素、氰基、硝基、C.sub.1-C.sub.4烷基、C.sub.1-C.sub.4卤代烷基、--X--C.sub.1-C.sub.4-烷基、C.sub.1-C.sub.4烷氧羰基、氨基、单-或双-(C.sub.1-C.sub.4烷基)氨基、氨基甲酰基、单-或双-(C.sub.1-C.sub.4烷基)氨基甲酰基、磺酰胺基、单-或双-(C.sub.1-C.sub.4烷基)磺酰胺基基团取代的苯基基团，或A--X--形成氨基基团--NR.sub.6 R.sub.7，E是亚甲基基团或氮，R.sub.1是氢、卤素、C.sub.1-C.sub.4烷基、C.sub.1-C.sub.4烷氧基、C.sub.1-C.sub.4卤代烷基、C.sub.1-C.sub.4卤代烷氧基、C.sub.2-C.sub.5烷氧基烷氧基、C.sub.1-C.sub.5烷硫基、C.sub.1-C.sub.5烷基亚硫酰基或C.sub.1-C.sub.5烷基磺酰基，R.sub.2是未取代或被1到3个卤素原子取代的C.sub.1-C.sub.3烷基，或是C.sub.1-C.sub.3烷氧基，R.sub.3是氢、卤素、氨基--NR.sub.4 R.sub.5，或是未取代或被1到3个卤素原子取代的C.sub.1-C.sub.3烷基，或是未取代或被甲氧基、乙氧基或1到3个卤素原子取代的C.sub.1-C.sub.4烷氧基，R.sub.4是氢或甲基，R.sub.5是氢、C.sub.1-C.sub.2烷基或甲氧基，R.sub.6和R.sub.7各自独立地是氢、C.sub.1-C.sub.4烷基、C.sub.3-C.sub.6烯基、C.sub.3-C.sub.6炔基、C.sub.3-C.sub.6烷氧基烷基、C.sub.1-C.sub.4氰基烷基，或两者与它们所连接的氮原子一起形成饱和的5-或6-成员杂环环系，该环系也可以包含氧、硫或--NR.sub.8基团，R.sub.8是氢、C.sub.1-C.sub.4烷基或苄基，X是氧、硫或亚硫酰基或磺酰基桥，以及这些化合物与胺、碱金属基或碱土金属基的盐具有良好的前和后除草和生长调节特性。

  公开号：

  US04579583A1

文献信息

• Neue Sulfonylharnstoffe
  申请人：CIBA-GEIGY AG

  公开号：EP0103543B1

  公开（公告）日：1987-09-30
• US4579583A
  申请人：——

  公开号：US4579583A

  公开（公告）日：1986-04-01
• US4690707A
  申请人：——

  公开号：US4690707A

  公开（公告）日：1987-09-01
• Novel sulfonylureas
  申请人：Ciba-Geigy Corporation

  公开号：US04579583A1

  公开（公告）日：1986-04-01

  The invention relates to N-pyridylsulfonyl-N'-pyrimidinyl- and -N'-triazinylureas of the formula I ##STR1## wherein A is a C.sub.3 -C.sub.6 alkynyl radical, a C.sub.1 -C.sub.6 alkyl radical which is substituted by halogen, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfinyl, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 haloalkylsulfinyl or C.sub.1 -C.sub.4 haloalkylsulfonyl, or is a C.sub.2 -C.sub.4 alkenyl radical which is unsubstituted or substituted as for C.sub.1 -C.sub.6 alkyl, or is a phenyl radical which is unsubstituted or substituted by halogen, cyano, nitro, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, an --X--C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 alkoxycarbonyl, amino, mono- or di-(C.sub.1 -C.sub.4 alkyl)amino, carbamoyl, mono- or di-(C.sub.1 -C.sub.4 alkyl)carbamoyl, sulfamoyl, mono- or di-(C.sub.1 -C.sub.4 alkyl)sulfamoyl radical or A--X-- forms an amino radical --NR.sub.6 R.sub.7, E is the methine group or nitrogen, R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.2 -C.sub.5 alkoxyalkoxy, C.sub.1 -C.sub.5 alkylthio, C.sub.1 -C.sub.5 alkylsulfinyl or C.sub.1 -C.sub.5 alkylsulfonyl, R.sub.2 is C.sub.1 -C.sub.3 alkyl which is unsubstituted or substituted by 1 to 3 halogen atoms, or is C.sub.1 -C.sub.3 alkoxy, R.sub.3 is hydrogen, halogen, an amino group --NR.sub.4 R.sub.5, or C.sub.1 -C.sub.3 alkyl which is unsubstituted or substituted by 1 to 3 halogen atoms, or is C.sub.1 -C.sub.4 alkoxy which is unsubstituted or substituted by methoxy, ethoxy or 1 to 3 halogen atoms, R.sub.4 is hydrogen or methyl, R.sub.5 is hydrogen, C.sub.1 -C.sub.2 alkyl or methoxy, R.sub.6 and R.sub.7 are each independently hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 alkynyl, C.sub.3 -C.sub.6 alkoxyalkyl, C.sub.1 -C.sub.4 cyanoalkyl, or both together with the nitrogen atom to which they are attached also form a saturated 5- or 6-membered heterocyclic ring system which may also contain oxygen, sulfur or an --NR.sub.8 radical, R.sub.8 is hydrogen, C.sub.1 -C.sub.4 alkyl or benzyl, and X is oxygen, sulfur, or a sulfinyl or sulfonyl bridge and to the salts thereof with amines, alkali metal bases or alkaline earth metal bases. These compounds have good pre- and postemergence selective herbicidal and growth regulating properties.

  本发明涉及公式I的N-吡啶磺酰基-N'-嘧啶基和-N'-三嗪基脲化合物，其中A是C.sub.3-C.sub.6炔基、被卤素取代的C.sub.1-C.sub.6烷基、C.sub.1-C.sub.4烷氧基、C.sub.1-C.sub.4烷基硫基、C.sub.1-C.sub.4烷基亚硫酰基、C.sub.1-C.sub.4烷基磺酰基、C.sub.1-C.sub.4卤代烷氧基、C.sub.1-C.sub.4卤代烷基硫基、C.sub.1-C.sub.4卤代烷基亚硫酰基或C.sub.1-C.sub.4卤代烷基磺酰基，或者是未取代或被C.sub.1-C.sub.6烷基取代的C.sub.2-C.sub.4烯基基团，或是未取代或被卤素、氰基、硝基、C.sub.1-C.sub.4烷基、C.sub.1-C.sub.4卤代烷基、--X--C.sub.1-C.sub.4-烷基、C.sub.1-C.sub.4烷氧羰基、氨基、单-或双-(C.sub.1-C.sub.4烷基)氨基、氨基甲酰基、单-或双-(C.sub.1-C.sub.4烷基)氨基甲酰基、磺酰胺基、单-或双-(C.sub.1-C.sub.4烷基)磺酰胺基基团取代的苯基基团，或A--X--形成氨基基团--NR.sub.6 R.sub.7，E是亚甲基基团或氮，R.sub.1是氢、卤素、C.sub.1-C.sub.4烷基、C.sub.1-C.sub.4烷氧基、C.sub.1-C.sub.4卤代烷基、C.sub.1-C.sub.4卤代烷氧基、C.sub.2-C.sub.5烷氧基烷氧基、C.sub.1-C.sub.5烷硫基、C.sub.1-C.sub.5烷基亚硫酰基或C.sub.1-C.sub.5烷基磺酰基，R.sub.2是未取代或被1到3个卤素原子取代的C.sub.1-C.sub.3烷基，或是C.sub.1-C.sub.3烷氧基，R.sub.3是氢、卤素、氨基--NR.sub.4 R.sub.5，或是未取代或被1到3个卤素原子取代的C.sub.1-C.sub.3烷基，或是未取代或被甲氧基、乙氧基或1到3个卤素原子取代的C.sub.1-C.sub.4烷氧基，R.sub.4是氢或甲基，R.sub.5是氢、C.sub.1-C.sub.2烷基或甲氧基，R.sub.6和R.sub.7各自独立地是氢、C.sub.1-C.sub.4烷基、C.sub.3-C.sub.6烯基、C.sub.3-C.sub.6炔基、C.sub.3-C.sub.6烷氧基烷基、C.sub.1-C.sub.4氰基烷基，或两者与它们所连接的氮原子一起形成饱和的5-或6-成员杂环环系，该环系也可以包含氧、硫或--NR.sub.8基团，R.sub.8是氢、C.sub.1-C.sub.4烷基或苄基，X是氧、硫或亚硫酰基或磺酰基桥，以及这些化合物与胺、碱金属基或碱土金属基的盐具有良好的前和后除草和生长调节特性。