(S)-(3-aminophenyl)-chloromethanol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (S)-(3-aminophenyl)-chloromethanol
• 化学式: C₇H₈ClNO
• 分子量: 157.6
• InChiKey: OSBIDRVYVLUTHL-SSDOTTSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  46.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• CONTINUOUS BIOTRANSFORMATION OF SUBSTITUTED AROMATIC CARBOXYLIC ACIDS TO THEIR SELECTIVE ALDEHYDES AND ALCOHOLS
  申请人：Privi Biotechnologies Pvt. Ltd.

  公开号：EP2890800A2

  公开（公告）日：2015-07-08
• [EN] CONTINUOUS BIOTRANSFORMATION OF SUBSTITUTED AROMATIC CARBOXYLIC ACIDS TO THEIR SELECTIVE ALDEHYDES AND ALCOHOLS<br/>[FR] BIOTRANSFORMATION CONTINUE D'ACIDES CARBOXYLIQUES AROMATIQUES SUBSTITUÉS EN LEURS ALDÉHYDES ET ALCOOLS SÉLECTIFS
  申请人：PRIVI BIOTECHNOLOGIES PRIVATE LTD

  公开号：WO2014045299A2

  公开（公告）日：2014-03-27

  The present invention discloses a novel method for biological reduction of the carboxylic acids to their corresponding aldehydes and/or alcohols with high productivity and high yield by using fungus in the category of basidiomycetes. This reduction is specific and selective for its functional group (-COOH), without affecting other functional group such as-R groups (- OH, -NH2, -alkyl, -alkyoxy) and their position, number on aromatic ring. The method of the invention relates to reduction of aryl acids to aldehyde and/or alcohols by employing a white rot fungus- Pycnoporus cinnabarinus, an organism of basidiomycete species, grown in vessel/ column. The biotransformation was performed in vessel/column/fermentor with pH control, dissolved oxygen, membrane system, product extractor is attached.