2-methyl-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-methyl-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide
• 化学式: C₁₄H₁₁N₃O₂S
• 分子量: 285.32
• InChiKey: PCHDWXRZIJKNSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  96.3
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] COMPOUNDS AND THEIR USES AS MIF INHIBITORS<br/>[FR] COMPOSÉS ET LEURS UTILISATIONS EN TANT QU'INHIBITEURS DE MIF
  申请人：NANJING IMMUNOPHAGE BIOTECH CO LTD

  公开号：WO2021258272A1

  公开（公告）日：2021-12-30

  The present invention provides compounds of Formula (I) which can be used as macrophage migration inhibitory factor (MIF) inhibitors; methods for the production of the compounds of the invention; pharmaceutical compositions comprising the compounds of the invention; as well as uses and methods for treating a disease mediated by MIF by administering the compounds of the invention.