4-[4-[(4-Methylphenyl)carbamoylamino]cyclohexyl]oxybenzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[4-[(4-Methylphenyl)carbamoylamino]cyclohexyl]oxybenzoic acid
• 英文别名: 4-[4-[(4-methylphenyl)carbamoylamino]cyclohexyl]oxybenzoic acid
• 化学式: C₂₁H₂₄N₂O₄
• 分子量: 368.4
• InChiKey: BZJSCBNITSXADX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  87.7
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• METHODS OF IMPROVING CELL-BASED THERAPY
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US20160008342A1

  公开（公告）日：2016-01-14

  Provided are methods for improving cell-based therapies by co-administration with an agent that increases the production and or levels of epoxygenated fatty acids, as well as kits, stents and patches for co-administering stem cells with an agent that increases the production and/or levels of epoxygenated fatty acids.
• METHODS OF INHIBITING PAIN
  申请人：The Regents of the University of California

  公开号：US20180125803A1

  公开（公告）日：2018-05-10

  Provided are methods and compositions for preventing, reducing, mitigating and treating pain, particularly neuropathic pain by the combined administration of an agent that increases EETs and an agent that reduces/inhibits endoplasmic reticulum (ER) stress.
• METHODS AND COMPOSITIONS FOR TREATING NEPHROPATHY
  申请人：The Regents of the University of California

  公开号：US20180185309A1

  公开（公告）日：2018-07-05

  Provided are compositions and methods for improving podocyte and kidney function and glucose homeostasis in diabetic and pre-diabetic states.