[Nitro(phenyl)methyl] propanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [Nitro(phenyl)methyl] propanoate
• 英文别名: [nitro(phenyl)methyl] propanoate
• 化学式: C10H11NO4
• 分子量: 209.2
• InChiKey: RRUBMROQHBOMQF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  72.1
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• ESTERS OF SHORT CHAINS FATTY ACIDS FOR USE IN THE TREATMENT OF IMMUNOGENIC DISORDERS
  申请人：Proponent Biotech GmbH

  公开号：EP2903608A1

  公开（公告）日：2015-08-12
• CARBOXYLIC ACIDS FOR EARLY CHILDHOOD APPLICATION
  申请人：Proponent Biotech GmbH

  公开号：EP3458044A1

  公开（公告）日：2019-03-27
• CARBOXYLIC ACID FOR TREATING/PREVENTING NASAL CONGESTION
  申请人：Proponent Biotech GmbH

  公开号：EP3458043A1

  公开（公告）日：2019-03-27
• [EN] ESTERS OF SHORT CHAINS FATTY ACIDS FOR USE IN THE TREATMENT OF IMMUNOGENIC DISORDERS<br/>[FR] ESTERS D'ACIDES GRAS À CHAÎNES COURTES POUR L'UTILISATION DANS LE TRAITEMENT DE TROUBLES IMMUNOGÈNES
  申请人：PROPONENT BIOTECH GMBH

  公开号：WO2014053592A1

  公开（公告）日：2014-04-10

  The present invention relates to short chain fatty acids (SCFA) for use in transmucosal administration to a subject for the prevention, attenuation or treatment of a disease or disorder associated with a compromised Th1 immune response and/or an unwanted Th2 or Th2-like immune response by modulating a Th2 immune response towards a Th1 immune response, particularly for the treatment, prevention and/or amelioration of viral infections and as an adjuvant for promoting the efficiency of vaccines and/or prevention of allergic diseases or disorders.
• [EN] CARBOXYLIC ACID FOR TREATING/PREVENTING NASAL CONGESTION<br/>[FR] ACIDE CARBOXYLIQUE POUR TRAITER/PRÉVENIR LA CONGESTION NASALE
  申请人：PROPONENT BIOTECH GMBH

  公开号：WO2017198702A1

  公开（公告）日：2017-11-23

  The present invention relates to a pharmaceutical composition comprising a carboxylic acid or a pharmaceutically acceptable salt thereof as active ingredient for use in treating and/or alleviating and/or preventing nasal congestion, a viral infectious disease of the respiratory tract or an inflammation of the throat. Furthermore, the present invention relates to a method for treating and/or alleviating and/or preventing nasal congestion, viral infections of the respiratory tract and/or inflammation of the throat in. a patient, comprising administering an effective amount of a carboxylic acid or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising a carboxylic acid or a pharmaceutically acceptable salt thereof to a patient in need thereof. In addition, the present invention relates to a method for alleviating the symptoms associated with nasal congestion, viral infections of the respiratory tract and/or inflammation of the throat comprising administering an effective amount of a carboxylic acid or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising a carboxylic acid or a pharmaceutically acceptable salt thereof to a patient in need thereof.