[3-[Hydroxy-[1-hydroxy-2-methyl-4-(4-octylphenyl)butan-2-yl]amino]-3-oxopropyl]-triphenylphosphanium;bromide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [3-[Hydroxy-[1-hydroxy-2-methyl-4-(4-octylphenyl)butan-2-yl]amino]-3-oxopropyl]-triphenylphosphanium;bromide
• 英文别名: [3-[hydroxy-[1-hydroxy-2-methyl-4-(4-octylphenyl)butan-2-yl]amino]-3-oxopropyl]-triphenylphosphanium;bromide
• 化学式: C40H51BrNO3P
• 分子量: 704.7
• InChiKey: QISCONQRPFSJSG-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  4.88
• 重原子数：
  46
• 可旋转键数：
  18
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE<br/>[FR] COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DE LA MALADIE PARKINSON
  申请人：UNIV TEXAS TECH SYSTEM

  公开号：WO2014063057A1

  公开（公告）日：2014-04-24

  The present invention provides a method for treating, alleviating, reversing or delaying progression of at least one symptom of Parkinson's Disease in a subject in need thereof by administering to the subject an effective amount of a 2-amino-2-[2-(4-octylphenyl)ethyl]propane-l,3-diol composition or a derivative thereof to treat at least one symptom of Parkinson's Disease.