4-[2-(1-Methylazetidin-1-ium-1-yl)ethyl]aniline

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[2-(1-Methylazetidin-1-ium-1-yl)ethyl]aniline
• 英文别名: 4-[2-(1-methylazetidin-1-ium-1-yl)ethyl]aniline
• 化学式: C12H19N2+
• 分子量: 191.29
• InChiKey: QAQODMXNIOWCTJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Radiofluorinated compounds and their preparation
  申请人：HAMMERSMITH IMANET LIMITED

  公开号：US20140127130A1

  公开（公告）日：2014-05-08

  The present invention provides a process for [ 18 F]-fluorination of biomolecules containing a primary amino group such as proteins and peptides and in particular of peptides. The invention further provides reagents for this process, in particular 18 F-labelled prosthetic groups for use in the preparation as well as non-labelled intermediates useful in the preparation of the [ 18 F]-labelled prosthetic groups. [ 18 F]-labelled compounds useful as radiopharmaceuticals, specifically for use in Positron Emission Tomography (PET) are also provided.