(3-Nitro-1-benzofuran-5-yl) 2-chloro-4-fluorobenzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3-Nitro-1-benzofuran-5-yl) 2-chloro-4-fluorobenzoate
• 英文别名: (3-nitro-1-benzofuran-5-yl) 2-chloro-4-fluorobenzoate
• 化学式: C15H7ClFNO5
• 分子量: 335.67
• InChiKey: ZVMMXPMXQLUNJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  85.3
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF EPSTEIN-BARR NUCLEAR ANTIGEN 1
  申请人：THE WISTAR INSTITUTE

  公开号：US20140113897A1

  公开（公告）日：2014-04-24

  The present invention embraces compounds that modulate the activity of Epstein-Barr Nuclear Antigen 1 (BBNA1) protein and use thereof in methods for treating latent Epstein-Barr virus infection. R 7 is a substituted or unsubstituted phenyl, pyridyl, or pyrimidinyl group. A pharmaceutical composition comprising a compound of the invention in admixture with a pharmaceutically acceptable carrier is also provide as are methods for modulating the activity of Epstein-Barr Nuclear Antigen 1 (EBNA1) protein and treating a latent EpsteinBarr virus infection with a composition of the present invention.
• US9309212B2
  申请人：——

  公开号：US9309212B2

  公开（公告）日：2016-04-12