1-Ethenylsulfonylethene;pyrrole-2,5-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 1-Ethenylsulfonylethene;pyrrole-2,5-dione
• 英文别名: 1-ethenylsulfonylethene;pyrrole-2,5-dione
• 化学式: C8H9NO4S
• 分子量: 215.23
• InChiKey: QWORBHXCZUJKFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.11
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  88.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Sulfated alginate hydrogels for cell culture and therapy
  申请人：ETH Zurich

  公开号：US10980887B2

  公开（公告）日：2021-04-20

  The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.

  本发明涉及一种提供包埋哺乳动物细胞的方法，包括以下步骤：提供水溶液中的硫酸藻酸盐；在凝胶化步骤中使硫酸藻酸盐反应形成水凝胶，提供前体细胞，在包埋步骤中将前体细胞包埋在硫酸化藻酸盐水凝胶中，从而得到硫酸化藻酸盐水凝胶包埋细胞。本发明还涉及硫酸化海藻酸盐水凝胶，以及由嵌入硫酸化海藻酸盐水凝胶的哺乳动物细胞组成的细胞移植物。
• SULFATED ALGINATE HYDROGELS FOR CELL CULTURE AND THERAPY
  申请人：ETH Zurich

  公开号：EP2916881A1

  公开（公告）日：2015-09-16
• US9937257B2
  申请人：——

  公开号：US9937257B2

  公开（公告）日：2018-04-10
• [EN] SULFATED ALGINATE HYDROGELS FOR CELL CULTURE AND THERAPY<br/>[FR] HYDROGELS À BASE D'ALGINATE SULFATÉ POUR LA CULTURE CELLULAIRE ET LA THÉRAPIE
  申请人：ETH ZUERICH

  公开号：WO2014072035A1

  公开（公告）日：2014-05-15

  The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.