1H-indol-5-yl hexadecanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: 1H-indol-5-yl hexadecanoate
• 化学式: C₂₄H₃₇NO₂
• 分子量: 371.563
• InChiKey: DRHTUORXELNNMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  27
• 可旋转键数：
  16
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  42.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1H-indol-5-yl hexadecanoate 、 1,3-dioxoisoindolin-2-yl 2-(1H-indol-3-yl)acetate 在 Ru(bpy)₂(PF₆)₂ 作用下， 以 二氯甲烷 为溶剂， 以48%的产率得到3-((1H-indol-3-yl)methyl)-1H-indol-5-yl palmitate
  参考文献：
  名称：

  二芳基甲烷的光催化氧化还原中性方法

  摘要：

  我们报告了吲哚-3-乙酸NHPI 酯与吲哚的可见光诱导的氧化还原-中性脱羧交叉偶联反应，使用 Ru 光敏剂来提供各种对称和不对称的 3,3'-双吲哚甲烷衍生物。此外，该反应很容易适用于制备多种二芳基甲烷衍生物。

  DOI：

  10.1021/acs.orglett.1c02523

文献信息

• System and method for serum based cancer detection
  申请人：CHEMIMAGE CORPORATION

  公开号：US11145411B2

  公开（公告）日：2021-10-12

  A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.

  一种用于分析生物样本（如干人血清）以确定疾病状态（如结直肠癌）的系统和方法。使用干燥样本有可能增强样本成分的局部浓缩和/或分割。该方法可包括照射生物样本的至少一个位置以产生多个相互作用光子，收集相互作用光子并生成至少一个代表生物样本的拉曼数据集。系统可包括一个照明光源，用于照射生物样本的至少一个位置并产生至少多个相互作用光子；至少一个反射镜，用于将相互作用光子导向检测器。检测器可配置为生成至少一个代表生物样本的拉曼数据集。该系统和方法可利用 FAST 设备进行多点分析，也可配置为使用线扫描配置分析样品。
• SYSTEM AND METHOD FOR SERUM BASED CANCER DETECTION
  申请人：ChemImage Corporation

  公开号：EP2917734A1

  公开（公告）日：2015-09-16
• [EN] SYSTEM AND METHOD FOR SERUM BASED CANCER DETECTION<br/>[FR] SYSTÈME ET PROCÉDÉ DE DÉTECTION DU CANCER BASÉE SUR DU SÉRUM
  申请人：CHEMIMAGE CORP

  公开号：WO2014074569A1

  公开（公告）日：2014-05-15

  A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.