2-Chloro-6-methyl-4-(nitrosomethyl)-1,2-dihydropyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-Chloro-6-methyl-4-(nitrosomethyl)-1,2-dihydropyridine
• 英文别名: 2-chloro-6-methyl-4-(nitrosomethyl)-1,2-dihydropyridine
• 化学式: C₇H₉ClN₂O
• 分子量: 172.61
• InChiKey: VQQKNIUAHDWJFE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  41.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] N-(PYRIDIN-2-YL)PYRIMIDIN-4-AMINE DERIVATIVES CONTAINING A SULFONE GROUP<br/>[FR] DÉRIVÉS N-(PYRIDIN-2-YL)PYRIMIDIN-4-AMINE CONTENANT UN GROUPE SULFONE
  申请人：BAYER PHARMA AG

  公开号：WO2014060493A2

  公开（公告）日：2014-04-24

  The present invention relates to N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfone group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).