N-[3-amino-6-[(4-fluorophenyl)methylamino]pyridin-2-yl]acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[3-amino-6-[(4-fluorophenyl)methylamino]pyridin-2-yl]acetamide
• 化学式: C₁₄H₁₅FN₄O
• 分子量: 274.29
• InChiKey: MMZDEDQJPXNLIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  80
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] COMPOSITIONS AND METHODS FOR THE TREATMENT OF PAIN AND NEUROLOGICAL DISEASES<br/>[FR] COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE LA DOULEUR ET DE MALADIES NEUROLOGIQUES
  申请人：KANDULA MAHESH

  公开号：WO2014068459A2

  公开（公告）日：2014-05-08

  The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of pain and neurological diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of partial-onset seizures, diabetic neuropathic pain, back pain and other orthopaedic uses, migraines, oncology, postoperative care, gynaecology, Creutzfeld- Jakob disease, multiple sclerosis, Batten disease, fibromyalgia, Alzheimer's disease, and multiple sclerosis.