2-[3-(4-Bromobenzoyl)phenyl]acetic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[3-(4-Bromobenzoyl)phenyl]acetic acid
• 英文别名: 2-[3-(4-bromobenzoyl)phenyl]acetic acid
• 化学式: C₁₅H₁₁BrO₃
• 分子量: 319.15
• InChiKey: QWAOZPAYELXRIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• AQUEOUS LIQUID COMPOSITION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID
  申请人：Bausch & Lomb Incorporated

  公开号：EP2919755A1

  公开（公告）日：2015-09-23
• [EN] AQUEOUS LIQUID COMPOSITION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID<br/>[FR] COMPOSITION AQUEUSE LIQUIDE CONTENANT DE L'ACIDE 2-AMINO-3-(4-BROMOBENZOYL)-PHÉNYLACÉTIQUE
  申请人：BAUSCH & LOMB

  公开号：WO2014078766A1

  公开（公告）日：2014-05-22

  An aqueous liquid composition comprising: (a) 2-amino-3-(4-bromobenzoyl)phenylacetic acid or its pharmacologically acceptable salt or hydrate; (b) a non-ionic surfactant; and (c) a preservative; wherein at least 90 percent of the original amount of said 2-amino-3-(4-bromobenzoyl)phenylacetic acid or pharmacologically acceptable salt or hydrate remains in the composition after storage at 60 °C, for 4 weeks. The composition can satisfy the preservative efficacy of US Pharmacopeia 35 (2012). The composition is useful for the treatment of ocular or nasal inflammation of diverse etiology.