The invention relates to methods of treating cancer or myeloproliferative diseases with a combination of a glutaminase inhibitor and an anticancer agent selected from cabozantinib, crizotinib, and axitinib. The invention further relates to methods of treating cancer or myeloproliferative diseases that are resistant to one or more anticancer agents.
本发明涉及用谷
氨酰胺酶
抑制剂和选自
卡博替尼、
克唑替尼和
阿西替尼的抗癌剂组合治疗癌症或骨髓增生性疾病的方法。本发明进一步涉及治疗对一种或多种抗癌剂耐药的癌症或骨髓增生性疾病的方法。