6-(2-Carbamoyl-5-ethenylphenyl)hexanoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-(2-Carbamoyl-5-ethenylphenyl)hexanoic acid
• 英文别名: 6-(2-carbamoyl-5-ethenylphenyl)hexanoic acid
• 化学式: C₁₅H₁₉NO₃
• 分子量: 261.32
• InChiKey: IPWYQZGHTJRBFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• USE OF CARDIOTROPHIN- 1 FOR THE TREATMENT OF METABOLIC DISEASES
  申请人：Proyecto de Biomedicina Cima, S.L.

  公开号：EP2397152B1

  公开（公告）日：2014-05-28
• PREVENTION AND/OR TREATMENT OF ISCHEMIA OR ISCHEMIA/REPERFUSION INJURY
  申请人：Fundació Institut de recerca de l'Hospital de la Santa Creu i Sant Pau

  公开号：EP3429610A1

  公开（公告）日：2019-01-23
• [EN] PREVENTION AND/OR TREATMENT OF ISCHEMIA OR ISCHEMIA/REPERFUSION INJURY<br/>[FR] PRÉVENTION ET/OU TRAITEMENT DE LÉSIONS D'ISCHÉMIE OU D'ISCHÉMIE/REPERFUSION
  申请人：INST CATALÀ DE CIÈNCIES CARDIOVASCULARS (ICCC)

  公开号：WO2017157958A1

  公开（公告）日：2017-09-21

  The present invention relates to pharmaceutical compositions comprising a compound selected from the group consisting of: a) a polypeptide of SEQ ID NO:1, b)a functionally equivalent variant of the polypeptide according to a), c) a polynucleotide encoding a) or b), d) a vector comprising a polynucleotide according to c), e) a cell capable of secreting into the medium a polypeptide according to a) or b), and f) a nanoparticle comprising the polypeptide according to a) or b)and a pharmaceutically acceptable excipient. The invention also relates to the use of said compounds or pharmaceutical compositions for treatment and/or prevention of ischemia injury or ischemia/reperfusion injury in a subject.