2-Benzamido-4-[3-(3-cyclopentyloxy-2-hydroxypropoxy)-2-hydroxypropyl]sulfanylbutanoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Benzamido-4-[3-(3-cyclopentyloxy-2-hydroxypropoxy)-2-hydroxypropyl]sulfanylbutanoic acid
• 英文别名: 2-benzamido-4-[3-(3-cyclopentyloxy-2-hydroxypropoxy)-2-hydroxypropyl]sulfanylbutanoic acid
• 化学式: C₂₂H₃₃NO₇S
• 分子量: 455.6
• InChiKey: RRAZKPRQHAVHOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  31
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  151
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• PROCESS FOR PRODUCTION AND PURIFICATION OF RECOMBINANT LYSOSOMAL ALPHA-MANNOSIDASE
  申请人：Chiesi Farmaceutici S.p.A.

  公开号：EP2538968B1

  公开（公告）日：2017-11-01
• PURIFICATION OF RECOMBINANT HUMAN GALACTOCEREBROSIDE BETA-GALACTOSIDASE (RHGALC)
  申请人：Chiesi Farmaceutici S.p.A.

  公开号：EP2920198B1

  公开（公告）日：2019-09-25
• PURIFICATION OF RECOMBINANT HUMAN GALACTOCEREBROSIDE B-GALACTOSIDASE (rhGALC)
  申请人：Chiesi Farmaceutici S.p.A.

  公开号：US20180112202A1

  公开（公告）日：2018-04-26

  The present invention relates to a process for purifying recombinant human Galactocerebroside β-Galactosidase (rhGALC) from a cell culture, wherein a fraction of said cell culture comprising rhGALC is subjected to chromatography on three distinct resins.
• [EN] PURIFICATION OF RECOMBINANT HUMAN GALACTOCEREBROSIDE &bgr;-GALACTOSIDASE (rhGALC)<br/>[FR] PURIFICATION DE GALACTOCÉREBROSIDE &Bgr;-GALACTOSIDASE HUMAINE RECOMBINANTE (RHGALC)
  申请人：ACE BIOSCIENCES AS

  公开号：WO2014075688A1

  公开（公告）日：2014-05-22

  The present invention relates to a process for purifying recombinant human Galactocerebroside β-Galactosidase (rhGALC) from a cell culture, wherein a fraction of said cell culture comprising rhGALC is subjected to chromatography on three distinct resins.