2-[1-[[4-[[4-(Fluoromethyl)benzoyl]amino]phenyl]methyl]-3,5-dimethylpyrazol-4-yl]acetic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[1-[[4-[[4-(Fluoromethyl)benzoyl]amino]phenyl]methyl]-3,5-dimethylpyrazol-4-yl]acetic acid
• 英文别名: 2-[1-[[4-[[4-(fluoromethyl)benzoyl]amino]phenyl]methyl]-3,5-dimethylpyrazol-4-yl]acetic acid
• 化学式: C₂₂H₂₂FN₃O₃
• 分子量: 395.4
• InChiKey: WJBSAKWIOYVHME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  29
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  84.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• PYRAZOLE COMPOUNDS FOR TREATING HAIRLOSS
  申请人：SCHNAPP Andreas

  公开号：US20140148484A1

  公开（公告）日：2014-05-29

  The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof for use in the treatment or prevention of hairloss, wherein W, L 1 , L 2 , X, L 3 , Y, R 1 and R 2 have one of the meanings as indicated in the specification and claims, to pharmaceutical compositions containing said compounds or pharmaceutically acceptable salts thereof, to the use of said compounds or pharmaceutically acceptable salts thereof for the manufacture of a medicament useful for the treatment or prevention of hairloss, to a method of treating or preventing hairloss as well as to a method of stimulating hair growth.