3-Methyl-1-[5-(3-methylpyrrolidin-1-yl)pentyl]pyrrolidine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 3-Methyl-1-[5-(3-methylpyrrolidin-1-yl)pentyl]pyrrolidine
• 英文别名: 3-methyl-1-[5-(3-methylpyrrolidin-1-yl)pentyl]pyrrolidine
• 化学式: C₁₅H₃₀N₂
• 分子量: 238.41
• InChiKey: QMKRQDNRTMJPLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• NOVEL HIGH AFFINITY BIVALENT HELICALLY CONSTRAINED PEPTIDE AGAINST CANCER
  申请人：Dhar Amlanjyoti

  公开号：US20140155331A1

  公开（公告）日：2014-06-05

  The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.
• US9408888B2
  申请人：——

  公开号：US9408888B2

  公开（公告）日：2016-08-09