1-(3-Ethoxy-4-phenylphenyl)-2-(methylamino)ethanol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(3-Ethoxy-4-phenylphenyl)-2-(methylamino)ethanol
• 英文别名: 1-(3-ethoxy-4-phenylphenyl)-2-(methylamino)ethanol
• 化学式: C₁₇H₂₁NO₂
• 分子量: 271.35
• InChiKey: GTSZRFLHXYRQGS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  41.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Absorption enhancers for drug administration
  申请人：AEGIS THERAPEUTICS, LLC

  公开号：US10265402B2

  公开（公告）日：2019-04-23

  The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. In various aspects, the invention provides compositions and methods for oral delivery in the form of a tablet.

  本发明提供了提高治疗剂在受试者体内的生物利用度的组合物和方法。这些组合物包括至少一种烷基糖苷和至少一种治疗剂，其中烷基糖苷的烷基链长度为约 10 至约 16 个碳原子。在各个方面，本发明提供了片剂形式的口服给药组合物和方法。
• Compositions for drug administration
  申请人：Aegis Therapeutics, LLC

  公开号：US10576156B2

  公开（公告）日：2020-03-03

  The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms.

  本发明提供了提高治疗剂在受试者体内的生物利用度的组合物和方法。组合物包括至少一种烷基糖苷和至少一种治疗剂，其中烷基糖苷的烷基链长约为 10 至 16 个碳原子。
• COMPOSITIONS FOR DRUG ADMINISTRATION
  申请人：Aegis Therapeutics, LLC

  公开号：EP3082817A1

  公开（公告）日：2016-10-26
• COMPOSITIONS FOR ORAL DRUG ADMINISTRATION
  申请人：Maggio Edward T.

  公开号：US20140162965A1

  公开（公告）日：2014-06-12

  The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. In various aspects, the invention provides compositions and methods for oral delivery in the form of a tablet.
• ABSORPTION ENHANCERS FOR DRUG ADMINISTRATION
  申请人：AEGIS THERAPEUTICS, LLC

  公开号：US20180221489A1

  公开（公告）日：2018-08-09

  The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. In various aspects, the invention provides compositions and methods for oral delivery in the form of a tablet.