N-dimethoxyphosphoryl-2-phenylacetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-dimethoxyphosphoryl-2-phenylacetamide
• 化学式: C₁₀H₁₄NO₄P
• 分子量: 243.2
• InChiKey: YZDDPDFOHUKGAJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  64.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• PROTEIN PRODUCTION ACCELERATOR
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP2889368A1

  公开（公告）日：2015-07-01

  The present invention relates to a protein production accelerating agent that has enabled to largely increase the produced amount of a desired protein by adding polysaccharides to a medium for animal cells containing a serum or serum alternative, and a production method of a protein using a medium containing the protein production accelerating agent.

  本发明涉及一种蛋白质生产促进剂，通过在含有血清或血清替代物的动物细胞培养基中添加多糖，可在很大程度上提高所需蛋白质的生产量；本发明还涉及一种使用含有蛋白质生产促进剂的培养基生产蛋白质的方法。
• MEDIUM COMPOSITION AND METHOD FOR PRODUCING RED BLOOD CELLS USING SAME
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP2987852A1

  公开（公告）日：2016-02-24

  The present invention provides a method of producing erythrocytes, including efficiently differentiating hematopoietic stem cells and/or a hematopoietic progenitor cells into erythrocytes by using a medium composition having an effect of homogeneously dispersing the hematopoietic stem cells and/or the hematopoietic progenitor cells and maintaining a floating state.

  本发明提供了一种生产红细胞的方法，包括通过使用具有均匀分散造血干细胞和/或造血祖细胞并保持漂浮状态效果的培养基组合物，将造血干细胞和/或造血祖细胞有效分化成红细胞。
• METHOD FOR PRODUCING CULTURE MEDIUM COMPOSITION
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP3098299A1

  公开（公告）日：2016-11-30

  The present invention provides a production method of a medium composition, including previously removing divalent metal cations contained in a polymer compound having an anionic functional group, preparing a dry powder of the polymer compound, and mixing the dry powder and the medium, and the like. The present invention also provides a purification method of a polymer compound having an anionic functional group, which includes mixing a suspension of the polymer compound having an anionic functional group in water and a cation exchanger that exchanges a divalent metal cation with a monovalent metal cation to give a polymer compound having an anionic functional group, which shows a reduced amount of contaminating divalent metal cations.

  本发明提供了一种培养基组合物的生产方法，包括事先除去具有阴离子官能团的聚合物化合物中所含的二价金属阳离子，制备聚合物化合物的干粉，以及将干粉和培养基混合等。本发明还提供了一种具有阴离子官能团的聚合物化合物的提纯方法，包括将具有阴离子官能团的聚合物化合物悬浮液与水和阳离子交换器混合，阳离子交换器将二价金属阳离子与一价金属阳离子交换，得到具有阴离子官能团的聚合物化合物，该聚合物化合物中的二价金属阳离子污染量有所减少。
• CULTURE MEDIUM COMPOSITION
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP3098300A1

  公开（公告）日：2016-11-30

  The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues without substantially increasing the viscosity of the solution by nanofibers which have been added to the solusion and uniformly dispersed in the liquid medium, and the like.

  本发明提供了一种细胞和/或组织的培养方法，包括通过使用具有防止细胞和/或组织沉淀效果的培养基组合物来培养悬浮状态下的细胞和/或组织，该培养基组合物是通过纳米纤维在不大幅增加溶液粘度的情况下基本保留细胞和/或组织而实现的，纳米纤维已被添加到溶液中并均匀地分散在液体培养基等中。
• METHOD FOR CELL RECOVERY
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP3192863A1

  公开（公告）日：2017-07-19

  The present invention provides a method of isolating cells or tissues from a culture preparation of the cells or tissues in a medium composition which enables culture of the cells or tissues in suspension, which comprises at least one step selected from the group consisting of the following (A), (B) and (C): (A) passing the culture preparation through a filter having fine pores having a pore diameter of 5 - 500 µm, (B) adding a chelator to the culture preparation, and (C) diluting the culture preparation with a physiological aqueous solution.

  本发明提供了一种从细胞或组织的培养制剂中分离细胞或组织的方法，该培养制剂的培养基成分能使细胞或组织悬浮培养，该方法包括至少一个步骤，该步骤选自由下列组成的组(A)、(B)和(C)： (A) 使培养液通过具有细孔的过滤器，细孔直径为 5 - 500 微米、 (B) 向培养液中添加螯合剂，以及 (C) 用生理水溶液稀释培养液。