(2S)-5-(3-tert-butyl-4,5-difluorophenyl)pentan-2-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2S)-5-(3-tert-butyl-4,5-difluorophenyl)pentan-2-amine
• 化学式: C₁₅H₂₃F₂N
• 分子量: 255.35
• InChiKey: DWARCCMQTGAXNU-JTQLQIEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Antimicrobial Compounds and Methods of Making and Using the Same
  申请人：Duffy Erin M.

  公开号：US20140163049A1

  公开（公告）日：2014-06-12

  The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals.

  本发明通常涉及抗微生物化合物领域以及其制备和使用方法。这些化合物对于治疗、预防和减少人类和动物微生物感染的风险非常有用。
• Antimicrobials and methods of making and using same
  申请人：BIOVERSYS AG

  公开号：US10934295B2

  公开（公告）日：2021-03-02

  The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I): or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer.

  本公开内容一般涉及抗微生物化合物领域及其制造和使用方法。这些化合物可用于治疗、预防、降低人和动物微生物感染的风险并延缓其发生。在一些实施方案中，本公开提供了式(I)化合物：或其同系物或该化合物或同系物的药学上可接受的盐。
• Antimicrobial Compounds And Methods Of Making And Using The Same
  申请人：Melinta Therapeutics, Inc.

  公开号：US20180065966A1

  公开（公告）日：2018-03-08

  The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.
• ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME
  申请人：DUFFY Erin M.

  公开号：US20190211018A1

  公开（公告）日：2019-07-11

  The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I): or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer.
• ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
  申请人：Melinta Therapeutics, Inc.

  公开号：US20190322668A1

  公开（公告）日：2019-10-24

  The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals.