4-[(E)-[[5-[3-[2-(2-propoxyethoxy)ethoxy]propylcarbamoyl]pyridin-2-yl]hydrazinylidene]methyl]benzoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-[(E)-[[5-[3-[2-(2-propoxyethoxy)ethoxy]propylcarbamoyl]pyridin-2-yl]hydrazinylidene]methyl]benzoic acid
• 化学式: C₂₄H₃₂N₄O₆
• 分子量: 472.5
• InChiKey: OWIDHFXTCZLZQU-WPWMEQJKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  34
• 可旋转键数：
  17
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  131
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• NOVEL HYDRAZONE-BASED AND OXIME-BASED FLUORESCENT AND CHROMOPHORIC/PRO-FLUORESCENT AND PRO-CHROMOPHORIC REAGENTS AND LINKERS
  申请人：Solulink Biosciences, Inc.

  公开号：US20140171635A1

  公开（公告）日：2014-06-19

  Novel Hydrazone-based Fluorescent and Pro-Fluorescent Reagents and Linkers, including conjugationally extended hydrazine compositions, fluorescent hydrazone compositions, methods of the formation of hydrazones from the reaction of conjugationally extended hydrazines with conjugationally extended carbonyls, and methods of their use in assays systems are described. Use of these conjugationally compositions for direct colorimetric and fluorometric assays wherein a chromophore or the fluorophore is incorporated into the linker that is positioned between a reactive linking moiety and a biotin molecule.