N-[4-[[hydroxy(dimethoxy)-lambda5-phosphanylidene]amino]sulfonylphenyl]acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[4-[[hydroxy(dimethoxy)-lambda5-phosphanylidene]amino]sulfonylphenyl]acetamide
• 英文别名: N-[4-[[hydroxy(dimethoxy)-λ5-phosphanylidene]amino]sulfonylphenyl]acetamide
• 化学式: C₁₀H₁₅N₂O₆PS
• 分子量: 322.28
• InChiKey: BYASEAQFEOLWPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  123
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Primers with Modified Phosphate and Base in Allele-Specific PCR
  申请人：Roche Molecular Systems, Inc.

  公开号：US20140170650A1

  公开（公告）日：2014-06-19

  The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having at least one selective nucleotide complementary to only one variant of the target sequence and incorporating both a nucleotide with a base covalently modified at the exocyclic amino group and a modified phosphate.
• US9382581B2
  申请人：——

  公开号：US9382581B2

  公开（公告）日：2016-07-05