N-[[3-[[bis(pyridin-2-ylmethyl)amino]methyl]-5-methoxyphenyl]methyl]-1-pyridin-2-yl-N-(pyridin-2-ylmethyl)methanamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[[3-[[bis(pyridin-2-ylmethyl)amino]methyl]-5-methoxyphenyl]methyl]-1-pyridin-2-yl-N-(pyridin-2-ylmethyl)methanamine
• 化学式: C₃₃H₃₄N₆O
• 分子量: 530.7
• InChiKey: UGUIBSJZUXBAMW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  40
• 可旋转键数：
  13
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  67.3
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• [EN] COMPOSITIONS AND METHODS OF DIAGNOSING OCULAR DISEASES<br/>[FR] COMPOSITIONS ET PROCÉDÉS DE DIAGNOSTIC DE MALADIES OCULAIRES
  申请人：MOLECULAR TARGETING TECHNOLOGIES INC

  公开号：WO2014092958A1

  公开（公告）日：2014-06-19

  The invention provides novel multi-modality probes for pathologic cell tracking which allow labeling of dying cells with new probes and tracking them via non-invasive imaging techniques to diagnose ocular diseases, determine disease progression and evaluate effectiveness of treatment. The molecular probes of the invention can be topically, locally, or systemically administered for diagnosing and monitoring improvement or progression of any ocular diseases.

  该发明提供了用于病理细胞追踪的新型多模态探针，允许使用新的探针标记垂死细胞，并通过非侵入性成像技术跟踪它们，以诊断眼部疾病、确定疾病进展并评估治疗效果。该发明的分子探针可通过局部、局部或全身给药用于诊断和监测任何眼部疾病的改善或进展。
• COMPOSITIONS AND METHODS OF DIAGNOSING OCULAR DISEASES
  申请人：MOLECULAR TARGETING TECHNOLOGIES, INC.

  公开号：US20150367004A1

  公开（公告）日：2015-12-24

  The invention provides novel multi-modality probes for pathologic cell tracking which allow labeling of dying cells with new probes and tracking them via non-invasive imaging techniques to diagnose ocular diseases, determine disease progression and evaluate effectiveness of treatment. The molecular probes of the invention can be topically, locally, or systemically administered for diagnosing and monitoring improvement or progression of any ocular diseases.