N-ethyl-2-(ethylaminomethyl)-1-phenylcyclopropane-1-carboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-ethyl-2-(ethylaminomethyl)-1-phenylcyclopropane-1-carboxamide
• 化学式: C₁₅H₂₂N₂O
• 分子量: 246.35
• InChiKey: PKHIDPJDLSAORB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  41.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• LEVOMILNACIPRAN-BASED DRUG FOR FUNCTIONAL RECOVERY AFTER ACUTE NEUROLOGICAL EVENTS
  申请人：Sokoloff Pierre

  公开号：US20140179794A1

  公开（公告）日：2014-06-26

  The present invention concerns the use of levomilnacipran as medicinal product in functional recovery after a cerebrovascular accident or traumatic brain injury. The pharmaceutical compositions containing levomilnacipran are exclusively those not containing dextromilnacipran to a proportion of more than 5% by weight of the levomilnacipran/dextromilnacipran mixture, to avoid compromising functional recovery due to the alpha1-blocking property of dextromilnacipran.