benzyl N-[4-[4-(3-aminopropyl)phenyl]butyl]carbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzyl N-[4-[4-(3-aminopropyl)phenyl]butyl]carbamate
• 化学式: C₂₁H₂₈N₂O₂
• 分子量: 340.5
• InChiKey: YOBGFEORAXSPRO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  25
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  64.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS
  申请人：Parion Sciences, Inc.

  公开号：EP2931711B1

  公开（公告）日：2017-08-02
• [EN] ARYLALKYL-AND ARYLOXYALKYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS<br/>[FR] COMPOSÉS BLOQUEURS DU CANAL SODIQUE ÉPITHÉLIAL À SUBSTITUTION ARYLALKYL- ET ARYLOXYALKYLE
  申请人：PARION SCIENCES INC

  公开号：WO2014099705A1

  公开（公告）日：2014-06-26

  The present invention relates to the compound of the formula or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.