2-[[2-[3-[11-Ethyl-16-(1-hexoxyethyl)-4-hydroxy-12,17,21,26-tetramethyl-7,23,24,25-tetrazahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,4,6,8(26),9,11,13(25),14,16,18(24),19-undecaen-22-yl]propanoyloxy]-3-hexadecanoyloxypropoxy]-methoxyphosphoryl]oxyethyl-trimethylazanium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 2-[[2-[3-[11-Ethyl-16-(1-hexoxyethyl)-4-hydroxy-12,17,21,26-tetramethyl-7,23,24,25-tetrazahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,4,6,8(26),9,11,13(25),14,16,18(24),19-undecaen-22-yl]propanoyloxy]-3-hexadecanoyloxypropoxy]-methoxyphosphoryl]oxyethyl-trimethylazanium
• 英文别名: 2-[[2-[3-[11-ethyl-16-(1-hexoxyethyl)-4-hydroxy-12,17,21,26-tetramethyl-7,23,24,25-tetrazahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,4,6,8(26),9,11,13(25),14,16,18(24),19-undecaen-22-yl]propanoyloxy]-3-hexadecanoyloxypropoxy]-methoxyphosphoryl]oxyethyl-trimethylazanium
• 化学式: C64H99N5O10P+
• 分子量: 1129.5
• InChiKey: JPGRRJAUFWCPHF-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  13.6
• 重原子数：
  80
• 可旋转键数：
  38
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  181
• 氢给体数：
  2
• 氢受体数：
  12

文献信息

• [EN] COMPOSITIONS AND METHOD FOR LIGHT TRIGGERED RELEASE OF MATERIALS FROM NANOVESICLES<br/>[FR] COMPOSITIONS ET PROCÉDÉ POUR LIBÉRATION DÉCLENCHÉE PAR LUMIÈRE DE MATIÈRES DEPUIS DES NANOVÉSICULES
  申请人：UNIV NEW YORK STATE RES FOUND

  公开号：WO2014100379A1

  公开（公告）日：2014-06-26

  Provided are compositions comprising porphyrin-phospholipid nanovesicles (PoP-NVs) which can be loaded with cargo. Methods for release of cargo from the PoP-NVs triggered by near infrared (NIR) light are also disclosed.