N-butyl-4-ethenylaniline

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-butyl-4-ethenylaniline
• 化学式: C₁₂H₁₇N
• 分子量: 175.27
• InChiKey: YETBHWCPUMVWOI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Molecularly imprinted polymers and their use as antidandruff agents
  申请人：L'ORÉAL

  公开号：US10772822B2

  公开（公告）日：2020-09-15

  The invention relates to a molecularly imprinted polymer obtained by polymerization of a mixture comprising a basic ethylene monomer having an amine group, a crosslinking agent comprising at least 2 polymerizable ethylene unsaturations, a porogenic solvent and a C14-C20 fatty acid. A cosmetic composition comprising such a polymer. A cosmetic process to prevent and/or treat dandruff of the scalp using such a polymer.

  本发明涉及一种分子印迹聚合物，它是通过聚合一种混合物而得到的，该混合物包括 具有胺基团的碱性乙烯单体、包含至少 2 个可聚合乙烯不饱和物的交联剂、致孔溶剂和 C14-C20 脂肪酸。一种包含这种聚合物的化妆品组合物。一种使用这种聚合物预防和/或治疗头皮屑的化妆品工艺。
• Fluorescent probes for monitoring voltage by photo-induced electron transfer
  申请人：The Regents of the University of California

  公开号：US11187660B2

  公开（公告）日：2021-11-30

  Compounds and methods for determining transmembrane potential, monitoring changes in transmembrane potential, and/or drug screening are provided. In one aspect, compounds of the invention have a structure according to the formula: E-M-A, wherein A is a fluorophore, selected from xanthenes, coumarins, cyanines, bimanes, and difuloroboradizaindacenes, charged at physiological pH; M is a molecular wire; and E is a hydrophobic moiety, wherein A and E are capable of being involved in a photo-induced, intramolecular electron transfer that quenches the fluorescence of A in response to a voltage condition. When in use, compounds of the invention are membrane-impermeant and oriented within the cell membrane such that the charged moiety localizes at the outer leaflet of the lipid bilayer and the hydrophobic moiety and molecular wire associate with the hydrophobic portion of the lipid bilayer. The rate of electron transfer, fluorescence intensity, and quenching are altered in response to changes in transmembrane potential.

  本发明提供了用于确定跨膜电位、监测跨膜电位变化和/或药物筛选的化合物和方法。在一个方面，本发明的化合物具有符合式的结构：E-M-A，其中 A 是荧光团，选自香蒽类、香豆素类、氰胺类、双烷类和二氟硼二氮杂环丁烯类，在生理 pH 值下带电；M 是分子线；E 是疏水基，其中 A 和 E 能够参与光诱导的分子内电子转移，在电压条件下淬灭 A 的荧光。使用时，本发明的化合物具有膜渗透性，并在细胞膜内定向，使带电分子位于脂质双分子层的外侧小叶，疏水分子和分子线与脂质双分子层的疏水部分结合。电子转移率、荧光强度和淬灭都会随着跨膜电位的变化而改变。
• MOLECULARLY IMPRINTED POLYMERS AND THEIR USE AS ANTIDANDRUFF AGENTS
  申请人：L'Oréal

  公开号：EP2938641A1

  公开（公告）日：2015-11-04
• FLUORESCENT PROBES FOR MONITORING VOLTAGE BY PHOTO-INDUCED ELECTRON TRANSFER
  申请人：The Regents of the University of California

  公开号：US20170315059A1

  公开（公告）日：2017-11-02

  Compounds and methods for determining transmembrane potential, monitoring changes in transmembrane potential, and/or drug screening are provided. In one aspect, compounds of the invention have a structure according to the formula: E-M-A, wherein A is a fluorophore, selected from xanthenes, coumarins, cyanines, bimanes, and difuloroboradizaindacenes, charged at physiological pH; M is a molecular wire; and E is a hydrophobic moiety, wherein A and E are capable of being involved in a photo-induced, intramolecular electron transfer that quenches the fluorescence of A in response to a voltage condition. When in use, compounds of the invention are membrane-impermeant and oriented within the cell membrane such that the charged moiety localizes at the outer leaflet of the lipid bilayer and the hydrophobic moiety and molecular wire associate with the hydrophobic portion of the lipid bilayer. The rate of electron transfer, fluorescence intensity, and quenching are altered in response to changes in transmembrane potential.
• US9651494B2
  申请人：——

  公开号：US9651494B2

  公开（公告）日：2017-05-16