4-{2-[4-(Dimethylamino)phenyl]vinyl}-1-hexadecylpyridinium

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-{2-[4-(Dimethylamino)phenyl]vinyl}-1-hexadecylpyridinium
• 英文别名: 4-[(E)-2-(1-hexadecylpyridin-1-ium-4-yl)ethenyl]-N,N-dimethylaniline
• 化学式: C31H49N2+
• 分子量: 449.7
• InChiKey: ZDKRXBKIYXWTIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  33
• 可旋转键数：
  18
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Polymeric Dye Ratiometric Sensor for Analyte Detection and Methods of Using the Same
  申请人：Becton, Dickinson and Company

  公开号：US20180364245A1

  公开（公告）日：2018-12-20

  Fluorogenic sensors for a target analyte are provided. The fluorogenic sensors can include a water soluble light harvesting multichromophore and a fluorogenic dye covalently linked to the multichromophore and in energy-receiving proximity therewith. Aspects of the fluorogenic sensors include selective recognition of the target analyte by chemical reaction or by specific binding. In some cases, the linked fluorogenic dye includes a lactone or spiro-lactone group that is configured to chemically react with a target analyte via lactone ring-opening to produce a fluorescent dye configured for excitation by the multichromophore. Also provided are labelled specific binding members that include the subject dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject fluorogenic sensors find use are provided. Systems, devices and kits for practicing the subject methods are provided.
• [EN] POLYMERIC DYE RATIOMETRIC SENSOR FOR ANALYTE DETECTION AND METHODS OF USING THE SAME<br/>[FR] CAPTEUR RATIOMÉTRIQUE DE COLORANT POLYMÈRE POUR LA DÉTECTION D'ANALYTES ET SES PROCÉDÉS D'UTILISATION
  申请人：BECTON DICKINSON CO

  公开号：WO2017105927A1

  公开（公告）日：2017-06-22

  Fluorogenic sensors for a target analyte are provided. The fluorogenic sensors can include a water soluble light harvesting multichromophore and a fluorogenic dye covalently linked to the multichromophore and in energy-receiving proximity therewith. Aspects of the fluorogenic sensors include selective recognition of the target analyte by chemical reaction or by specific binding. In some cases, the linked fluorogenic dye includes a lactone or spiro-lactone group that is configured to chemically react with a target analyte via lactone ring-opening to produce a fluorescent dye configured for excitation by the multichromophore. Also provided are labelled specific binding members that include the subject dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject fluorogenic sensors find use are provided. Systems, devices and kits for practicing the subject methods are provided.