3-[[6-[[2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]-2-(hydroxymethyl)hexoxy]-hydroxyphosphoryl]oxypropyl [2-[3-[3-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]prop-1-en-2-ylamino]propanoylamino]-3-hydroxypropyl] hydrogen phosphate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-[[6-[[2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]-2-(hydroxymethyl)hexoxy]-hydroxyphosphoryl]oxypropyl [2-[3-[3-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]prop-1-en-2-ylamino]propanoylamino]-3-hydroxypropyl] hydrogen phosphate
• 英文别名: 3-[[6-[[2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]-2-(hydroxymethyl)hexoxy]-hydroxyphosphoryl]oxypropyl [2-[3-[3-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]prop-1-en-2-ylamino]propanoylamino]-3-hydroxypropyl] hydrogen phosphate
• 化学式: C₄₃H₅₉Cl₄N₃O₁₆P₂
• 分子量: 1077.7
• InChiKey: LMJWPWLGPMABHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  68
• 可旋转键数：
  36
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.49
• 拓扑面积：
  275
• 氢给体数：
  7
• 氢受体数：
  17

文献信息

• [EN] PROTEIN BIOSENSORS, CROSS REACTIVE SENSOR ARRAYS AND METHODS OF USE THEREOF<br/>[FR] BIOCAPTEURS PROTÉINIQUES, RÉSEAUX DE CAPTEURS À RÉACTION CROISÉE ET PROCÉDÉS D'UTILISATION CORRESPONDANTS
  申请人：YEDA RES & DEV

  公开号：WO2014102806A1

  公开（公告）日：2014-07-03

  The present invention is directed to fluorescent protein biosensors based on oligonucleotide cross reactive sensor arrays including a selective and a non-selective protein binding domain for protein detection. Interaction of different protein isoforms with the sensors of this invention yields a unique optical signature for each protein. The unique optical signature allows differentiating between closely related protein isoforms and diagnosing diseases and disorders associated with the proteins also in biofluids.