3-(5-Methoxypyrazin-2-yl)-2-(1-methylimidazol-4-yl)-6-(trifluoromethoxy)imidazo[4,5-b]pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: 3-(5-Methoxypyrazin-2-yl)-2-(1-methylimidazol-4-yl)-6-(trifluoromethoxy)imidazo[4,5-b]pyridine
• 英文别名: 3-(5-methoxypyrazin-2-yl)-2-(1-methylimidazol-4-yl)-6-(trifluoromethoxy)imidazo[4,5-b]pyridine
• 化学式: C₁₆H₁₂F₃N₇O₂
• 分子量: 391.31
• InChiKey: HZLXLDGNJXSWMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  92.8
• 氢给体数：
  0
• 氢受体数：
  10

文献信息

• NOVEL ANTIPLATELET AGENT
  申请人：MITSUBISHI TANABE PHARMA CORPORATION

  公开号：US20140194407A1

  公开（公告）日：2014-07-10

  The present invention relates to a novel antiplatelet agent and a novel compound which is an active ingredient for the agent. The present invention provides the antiplatelet agent comprising a compound represented by the formula I: wherein, X is N, or CR 1d , X b1 -X b5 are the same or different, and are nitrogen or carbon, R 1a -R 1d are the same or different, and are hydrogen, an optionally substituted alkyl, an optionally substituted alkoxy, an optionally substituted alkylthio, an alkenyl, a cycloalkyl, a halogen, cyano, or hydroxyl or optionally substituted by 1 or 2 alkylamino, R 2 is an optionally substituted aryl or an optionally substituted heteroaryl, R 3 is an optionally substituted aryl or an optionally substituted heteroaryl, or pharmaceutically acceptable salt thereof as an active ingredient.
• US9533983B2
  申请人：——

  公开号：US9533983B2

  公开（公告）日：2017-01-03