Benzamide, N,N'-(oxydi-4,1-phenylene)bis[3-nitro- | 111256-75-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzamide, N,N'-(oxydi-4,1-phenylene)bis[3-nitro-
• 英文别名: 3-nitro-N-[4-[4-[(3-nitrobenzoyl)amino]phenoxy]phenyl]benzamide
• CAS: 111256-75-8
• 化学式: C26H18N4O7
• 分子量: 498.4
• InChiKey: QJBXLWSXFIFIBS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  37
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  159
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Entry inhibitors of the hiv virus
  申请人：Van Acker Lodewijk August Koenraad

  公开号：US20070066623A1

  公开（公告）日：2007-03-22

  The present invention relates to small molecules as entry inhibitors of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors with other anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS.
• US8268885B2
  申请人：——

  公开号：US8268885B2

  公开（公告）日：2012-09-18