申请人:Aminex Therapeutics, Inc.
公开号:EP3785706A1
公开(公告)日:2021-03-03
Disclosed herein are pharmaceutical salts of a cationic protonated polyamine pharmaceutical agent and an anionic organic carboxylate which is hydrophobic when in protonated form, particularly suited for oral administration, where these salts have good bioavailability in solid dosage forms and may be used in the treatment of cancer and other medical conditions for which the pharmaceutical agent is intended.
本文公开了阳离子质子化多胺药剂和阴离子有机羧酸盐的药剂盐,后者在质子化形式时具有疏水性,特别适合口服给药,这些盐在固体剂型中具有良好的生物利用度,可用于治疗癌症和药剂所针对的其他病症。